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GATA4 GATA binding protein 4 [ Gallus gallus (chicken) ]

Gene ID: 396392, updated on 10-Oct-2024

Summary

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Symbol
GATA4provided by CGNC
Full Name
GATA binding protein 4provided by CGNC
Primary source
CGNC:12483
See related
Ensembl:ENSGALG00010011322
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
GATA-4
Orthologs
human mouse all
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Genomic context

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See GATA4 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
8
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 3 NC_052534.1 (107126694..107154434)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 3 NC_052575.1 (106889839..106917623)

Chromosome 3 - NC_052534.1Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 167, member A Neighboring gene uncharacterized LOC124417865 Neighboring gene BLK proto-oncogene, Src family tyrosine kinase Neighboring gene uncharacterized LOC100858393 Neighboring gene nei like DNA glycosylase 2 Neighboring gene farnesyl-diphosphate farnesyltransferase 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identification and biological characterization of chicken embryonic cardiac progenitor cells. Bai C, et al. Cell Prolif, 2013 Apr. PMID 23510478, Free PMC Article
  2. Gene expression of FK506-binding proteins 12.6 and 12 during chicken development. Yazawa S, et al. Comp Biochem Physiol A Mol Integr Physiol, 2003 Oct. PMID 14511757
  3. GATA-4/5/6, a subfamily of three transcription factors transcribed in developing heart and gut. Laverriere AC, et al. J Biol Chem, 1994 Sep 16. PMID 8083222
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  5. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell fate commitment IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
transcription factor GATA-4
Names
GATA-binding factor 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001293106.2 → NP_001280035.2  transcription factor GATA-4 isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000070
    UniProtKB/TrEMBL
    A0A8V0Y8V4
    Related
    ENSGALP00010015400.1, ENSGALT00010027064.1
    Conserved Domains (2) summary
    cd00202
    Location:240 → 291
    ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
    pfam05349
    Location:1 → 175
    GATA-N; GATA-type transcription activator, N-terminal

  2. NM_001397478.1 → NP_001384407.1  transcription factor GATA-4 isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000070
    Conserved Domains (2) summary
    cd00202
    Location:241 → 292
    ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
    pfam05349
    Location:1 → 175
    GATA-N; GATA-type transcription activator, N-terminal

  3. NM_001397479.1 → NP_001384408.1  transcription factor GATA-4 isoform 3

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000070

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052534.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    107126694..107154434
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046938577.1 → XP_046794533.1  transcription factor GATA-4 isoform X1

  2. XM_046938576.1 → XP_046794532.1  transcription factor GATA-4 isoform X1

  3. XM_046938578.1 → XP_046794534.1  transcription factor GATA-4 isoform X2

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052575.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    106889839..106917623
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046913311.1 → XP_046769267.1  transcription factor GATA-4 isoform X1

  2. XM_046913310.1 → XP_046769266.1  transcription factor GATA-4 isoform X1

  3. XM_046913312.1 → XP_046769268.1  transcription factor GATA-4 isoform X2

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P43691.1 GenPept UniProtKB/Swiss-Prot:P43691

Gene LinkOut

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Molecular Biology Databases
Research Materials