MST1 macrophage stimulating 1 (hepatocyte growth factor-like) [Gallus gallus (chicken)] - Gene

Summary

Official Symbol: MST1provided by CGNC
Official Full Name: macrophage stimulating 1 (hepatocyte growth factor-like)provided by CGNC
Primary source: CGNC:49667
See related: Ensembl:ENSGALG00010027291
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as: HGF1/MSP
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 12

Exon count:: 18

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	12	NC_052543.1 (2645277..2649390)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	12	NC_052584.1 (2662702..2666814)

Chromosome 12 - NC_052543.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables receptor tyrosine kinase binding	IEA Inferred from Electronic Annotation more info	PubMed
enables serine-type endopeptidase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in proteolysis	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of receptor signaling pathway via JAK-STAT	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in extracellular space	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: hepatocyte growth factor-like protein

Names: hepatocyte growth factor-like/macrophage stimulating protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001396436.1 → NP_001383365.1 hepatocyte growth factor-like protein isoform 1 precursor

Status: VALIDATED

Source sequence(s)

JAENSK010000251

UniProtKB/TrEMBL

A0A8V1AB22, Q90865

Related

ENSGALP00010040438.1, ENSGALT00010066172.1

Conserved Domains (3) summary

smart00130
Location:365 → 447

KR; Kringle domain

cd00190
Location:478 → 701

Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...

cd01099
Location:23 → 102

PAN_AP_HGF; Subfamily of PAN/APPLE-like domains; present in N-terminal (N) domains of plasminogen/hepatocyte growth factor proteins, and various proteins found in Bilateria, such as leech anti-platelet proteins. PAN/APPLE domains fulfill diverse biological functions ...
NM_205213.2 → NP_990544.2 hepatocyte growth factor-like protein isoform 2 precursor

Status: VALIDATED

Source sequence(s)

JAENSK010000251

UniProtKB/TrEMBL

Q90865

Related

ENSGALP00010040435.1, ENSGALT00010066170.1

Conserved Domains (3) summary

smart00130
Location:364 → 446

KR; Kringle domain

cd00190
Location:477 → 700

Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...

cd01099
Location:23 → 102

PAN_AP_HGF; Subfamily of PAN/APPLE-like domains; present in N-terminal (N) domains of plasminogen/hepatocyte growth factor proteins, and various proteins found in Bilateria, such as leech anti-platelet proteins. PAN/APPLE domains fulfill diverse biological functions ...