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LAMB4 laminin subunit beta 4 [ Gallus gallus (chicken) ]

Gene ID: 396076, updated on 10-Oct-2024

Summary

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Symbol
LAMB4provided by CGNC
Full Name
laminin subunit beta 4provided by CGNC
Primary source
CGNC:5987
See related
Ensembl:ENSGALG00010010829
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human all
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Genomic context

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See LAMB4 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
37
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 1 NC_052532.1 (15111982..15165811, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 1 NC_052573.1 (15247241..15303379, complement)

Chromosome 1 - NC_052532.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121108798 Neighboring gene dihydrolipoamide dehydrogenase Neighboring gene laminin subunit beta 1 Neighboring gene uncharacterized LOC112533030 Neighboring gene ERGIC and golgi 2 Neighboring gene leucine rich repeat kinase 2 Neighboring gene uncharacterized LOC121108850 Neighboring gene solute carrier family 2 member 13

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Regulated expression of a novel laminin beta subunit during the development of the chick embryo. Ybot-Gonzalez P, et al. Differentiation, 1995 Nov. PMID 8575643
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables extracellular matrix structural constituent IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in axon guidance IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in basement membrane assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in substrate adhesion-dependent cell spreading IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in basement membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of laminin complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
laminin subunit beta-4
Names
laminin beta x subunit
laminin, beta 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001199313.2 → NP_001186242.2  laminin subunit beta-4

    Status: PROVISIONAL

    Source sequence(s)
    JAENSK010000012
    UniProtKB/TrEMBL
    A0A8V0YAI8
    Related
    ENSGALP00010014622.1, ENSGALT00010025960.1

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    15111982..15165811 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040659207.2 → XP_040515141.1  laminin subunit beta-4 isoform X2

    UniProtKB/TrEMBL
    A0A8V0Y6P1
    Conserved Domains (6) summary
    smart00180
    Location:1129 → 1174
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    COG1196
    Location:1232 → 1775
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd00055
    Location:865 → 907
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00185
    Location:943 → 987
    TNFRSF; CRD2 [structural motif]
    cl02806
    Location:26 → 266
    Laminin_N; Laminin N-terminal (Domain VI)
    cl22855
    Location:921 → 1006
    TNFRSF; Tumor necrosis factor receptor superfamily (TNFRSF)

  2. XM_040659127.2 → XP_040515061.1  laminin subunit beta-4 isoform X1

    UniProtKB/TrEMBL
    A0A8V0Y6P1
    Conserved Domains (6) summary
    smart00180
    Location:1129 → 1174
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    COG1196
    Location:1232 → 1801
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd00055
    Location:865 → 907
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00185
    Location:943 → 987
    TNFRSF; CRD2 [structural motif]
    cl02806
    Location:26 → 266
    Laminin_N; Laminin N-terminal (Domain VI)
    cl22855
    Location:921 → 1006
    TNFRSF; Tumor necrosis factor receptor superfamily (TNFRSF)

  3. XM_040659047.2 → XP_040514981.1  laminin subunit beta-4 isoform X1

    UniProtKB/TrEMBL
    A0A8V0Y6P1
    Conserved Domains (6) summary
    smart00180
    Location:1129 → 1174
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    COG1196
    Location:1232 → 1801
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd00055
    Location:865 → 907
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00185
    Location:943 → 987
    TNFRSF; CRD2 [structural motif]
    cl02806
    Location:26 → 266
    Laminin_N; Laminin N-terminal (Domain VI)
    cl22855
    Location:921 → 1006
    TNFRSF; Tumor necrosis factor receptor superfamily (TNFRSF)

  4. XM_040659283.2 → XP_040515217.1  laminin subunit beta-4 isoform X3

    UniProtKB/TrEMBL
    A0A8V0Y6P1
    Conserved Domains (6) summary
    smart00180
    Location:986 → 1031
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    COG1196
    Location:1089 → 1658
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd00055
    Location:722 → 764
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00185
    Location:800 → 844
    TNFRSF; CRD2 [structural motif]
    cl02806
    Location:1 → 123
    Laminin_N; Laminin N-terminal (Domain VI)
    cl22855
    Location:778 → 863
    TNFRSF; Tumor necrosis factor receptor superfamily (TNFRSF)

  5. XM_040659351.2 → XP_040515285.1  laminin subunit beta-4 isoform X4

    UniProtKB/TrEMBL
    A0A8V0Y6P1
    Conserved Domains (6) summary
    smart00180
    Location:904 → 949
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    COG1196
    Location:1007 → 1573
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd00055
    Location:640 → 682
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00185
    Location:718 → 762
    TNFRSF; CRD2 [structural motif]
    cl02806
    Location:1 → 41
    Laminin_N; Laminin N-terminal (Domain VI)
    cl22855
    Location:696 → 781
    TNFRSF; Tumor necrosis factor receptor superfamily (TNFRSF)

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    15247241..15303379 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046906781.1 → XP_046762737.1  laminin subunit beta-4 isoform X1

  2. XM_046906782.1 → XP_046762738.1  laminin subunit beta-4 isoform X2

  3. XM_046906780.1 → XP_046762736.1  laminin subunit beta-4 isoform X1

Nucleotide Protein
Heading Accession and Version

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