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MYL3 myosin, light chain 3, alkali; ventricular, skeletal, slow [ Gallus gallus (chicken) ]

Gene ID: 396067, updated on 10-Oct-2024

Summary

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Official Symbol
MYL3provided by CGNC
Official Full Name
myosin, light chain 3, alkali; ventricular, skeletal, slowprovided by CGNC
Primary source
CGNC:49636
See related
Ensembl:ENSGALG00010025568
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
MLC; MLC1c/1s
Orthologs
human mouse all
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Genomic context

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See MYL3 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
8
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 2 NC_052533.1 (3449268..3483955, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 2 NC_052574.1 (3452819..3487514, complement)

Chromosome 2 - NC_052533.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121109758 Neighboring gene uncharacterized LOC121109759 Neighboring gene uncharacterized LOC101752077 Neighboring gene parathyroid hormone 2 receptor Neighboring gene uncharacterized LOC121109760

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Novel sensors of the regulatory switch on the regulatory light chain of smooth muscle Myosin. Mazhari SM, et al. J Biol Chem, 2004 Sep 17. PMID 15262959
  2. Amino-acid sequence of the L-1 light chain of chicken cardiac-muscle myosin. Maita T, et al. Eur J Biochem, 1980 Jun. PMID 6772448
  3. Single chicken cardiac myosin alkali light-chain gene generates two different mRNAs by alternative splicing of a complex exon. Nakamura S, et al. J Mol Biol, 1988 Oct 20. PMID 3210243
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  5. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. direct coupling of nucleotide binding to conformational changes in the N terminus of the regulatory light chain.
    Title: Novel sensors of the regulatory switch on the regulatory light chain of smooth muscle Myosin.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of myosin II complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
myosin light chain 1, cardiac muscle
Names
cardiac muscle
light polypeptide 3
myosin alkali light chain
myosin light chain A1
myosin light chain alkali 1
myosin, light polypeptide 3, alkali; ventricular, skeletal, slow
slow skeletal ventricular myosin alkali light chain 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_205159.2 → NP_990490.2  myosin light chain 1, cardiac muscle

    Status: PROVISIONAL

    Source sequence(s)
    JAENSK010000035
    UniProtKB/Swiss-Prot
    P02606
    UniProtKB/TrEMBL
    F1P5V6, R4GM29
    Related
    ENSGALP00010038565.1, ENSGALT00010062381.1
    Conserved Domains (1) summary
    PTZ00184
    Location:44 → 194
    PTZ00184; calmodulin; Provisional

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052533.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    3449268..3483955 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015281050.4 → XP_015136536.1  myosin light chain 1, cardiac muscle isoform X1

    UniProtKB/Swiss-Prot
    P02606
    UniProtKB/TrEMBL
    F1P5V6, R4GM29
    Conserved Domains (1) summary
    PTZ00184
    Location:44 → 194
    PTZ00184; calmodulin; Provisional

  2. XM_015281049.4 → XP_015136535.1  myosin light chain 1, cardiac muscle isoform X1

    UniProtKB/Swiss-Prot
    P02606
    UniProtKB/TrEMBL
    F1P5V6, R4GM29
    Conserved Domains (1) summary
    PTZ00184
    Location:44 → 194
    PTZ00184; calmodulin; Provisional

  3. XM_040676324.1 → XP_040532258.1  myosin light chain 1, cardiac muscle isoform X2

    Conserved Domains (1) summary
    PTZ00184
    Location:8 → 158
    PTZ00184; calmodulin; Provisional

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052574.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    3452819..3487514 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046910421.1 → XP_046766377.1  myosin light chain 1, cardiac muscle isoform X1

    UniProtKB/TrEMBL
    F1P5V6, R4GM29

  2. XM_046910420.1 → XP_046766376.1  myosin light chain 1, cardiac muscle isoform X1

    UniProtKB/TrEMBL
    F1P5V6, R4GM29

  3. XM_046910422.1 → XP_046766378.1  myosin light chain 1, cardiac muscle isoform X2

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P02606.3 GenPept UniProtKB/Swiss-Prot:P02606

Gene LinkOut

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