TYRP1 tyrosinase related protein 1 [Gallus gallus (chicken)] - Gene

Summary

Symbol: TYRP1provided by CGNC
Full Name: tyrosinase related protein 1provided by CGNC
Primary source: CGNC:11314
See related: Ensembl:ENSGALG00010014092
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as: TRP1; TRP-1
Orthologs: human mouse all
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Genomic context

Location:: chromosome: Z

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	Z	NC_052572.1 (31227860..31238589)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	Z	NC_059536.1 (31227860..31238589)

Chromosome Z - NC_052572.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

first TYRP1 mutation described in the chicken
Title: A missense mutation in TYRP1 causes the chocolate plumage color in chicken and alters melanosome structure.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables oxidoreductase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in melanocyte differentiation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in melanosome organization	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in melanosome	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: 5,6-dihydroxyindole-2-carboxylic acid oxidase

Names: DHICA oxidase

NP_990376.2

EC 1.14.18.-

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_205045.3 → NP_990376.2 5,6-dihydroxyindole-2-carboxylic acid oxidase precursor

Status: VALIDATED

Source sequence(s)

JAENSK010000092

UniProtKB/Swiss-Prot

O57405

UniProtKB/TrEMBL

F1NXQ4

Related

ENSGALP00010019896.1, ENSGALT00010033822.1

Conserved Domains (1) summary

pfam00264
Location:182 → 416

Tyrosinase; Common central domain of tyrosinase