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F10 coagulation factor X [ Gallus gallus (chicken) ]

Gene ID: 395876, updated on 17-Aug-2024

Summary

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Official Symbol
F10provided by CGNC
Official Full Name
coagulation factor Xprovided by CGNC
Primary source
CGNC:13760
See related
Ensembl:ENSGALG00010014766
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
FX
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Genomic context

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See F10 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
8
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 1 NC_052532.1 (137593836..137606492, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 1 NC_052573.1 (137593122..137605778, complement)

Chromosome 1 - NC_052532.1Genomic Context describing neighboring genes Neighboring gene PCI domain containing 2 Neighboring gene coagulation factor X-like Neighboring gene protein Z, vitamin K dependent plasma glycoprotein Neighboring gene coagulation factor VII Neighboring gene MCF.2 cell line derived transforming sequence like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. An endoprotease homologous to the blood clotting factor X as a determinant of viral tropism in chick embryo. Gotoh B, et al. EMBO J, 1990 Dec. PMID 2174359, Free PMC Article
  2. Primary structure of the virus activating protease from chick embryo. Its identity with the blood clotting factor Xa. Suzuki H, et al. FEBS Lett, 1991 Jun 3. PMID 2044767
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in blood coagulation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
coagulation factor X
Names
VAP
factor XA light chain
stuart factor
virus activating protease
NP_990353.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_205022.2 → NP_990353.1  coagulation factor X precursor

    See identical proteins and their annotated locations for NP_990353.1

    Status: PROVISIONAL

    Source sequence(s)
    JAENSK010000025
    UniProtKB/Swiss-Prot
    P25155
    UniProtKB/TrEMBL
    A0A8V0YPR3
    Related
    ENSGALP00010020645.1, ENSGALT00010035531.1
    Conserved Domains (5) summary
    smart00020
    Location:240 → 468
    Tryp_SPc; Trypsin-like serine protease
    smart00069
    Location:22 → 85
    GLA; Domain containing Gla (gamma-carboxyglutamate) residues
    cd00054
    Location:86 → 122
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00190
    Location:241 → 471
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam14670
    Location:129 → 167
    FXa_inhibition; Coagulation Factor Xa inhibitory site

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    137593836..137606492 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    137593122..137605778 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P25155.1 GenPept UniProtKB/Swiss-Prot:P25155

Gene LinkOut

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