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HESX1 HESX homeobox 1 [ Gallus gallus (chicken) ]

Gene ID: 395864, updated on 17-Aug-2024

Summary

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Symbol
HESX1provided by CGNC
Full Name
HESX homeobox 1provided by CGNC
Primary source
CGNC:4101
See related
Ensembl:ENSGALG00010027046
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
GANF
Orthologs
human mouse all
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Genomic context

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See HESX1 in Genome Data Viewer
Location:
chromosome: 12
Exon count:
9
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 12 NC_052543.1 (8781747..8791269, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 12 NC_052584.1 (8809327..8818539, complement)

Chromosome 12 - NC_052543.1Genomic Context describing neighboring genes Neighboring gene Rho guanine nucleotide exchange factor 3 Neighboring gene uncharacterized LOC124417171 Neighboring gene interleukin 17 receptor D Neighboring gene adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 Neighboring gene ankyrin repeat and SOCS box containing 14 Neighboring gene dynein, axonemal, heavy chain 12

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Anf: a novel class of vertebrate homeobox genes expressed at the anterior end of the main embryonic axis. Kazanskaya OV, et al. Gene, 1997 Oct 24. PMID 9373136
  2. Involvement of Pax6 and Otx2 in the forebrain-specific regulation of the vertebrate homeobox gene ANF/Hesx1. Spieler D, et al. Dev Biol, 2004 May 15. PMID 15110720
  3. Multiplex display polymerase chain reaction amplifies and resolves related sequences sharing a single moderately conserved domain. Peale FV Jr, et al. Anal Biochem, 1998 Feb 15. PMID 9473273
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in forebrain development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in pituitary gland development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
homeobox protein ANF-1
Names
anterior neural fold protein
homeo box (expressed in ES cells) 1
homeobox protein GANF
homeobox, ES cell expressed 1
homeodomain-containing protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_205012.3 → NP_990343.3  homeobox protein ANF-1

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000252
    UniProtKB/Swiss-Prot
    P79775
    UniProtKB/TrEMBL
    A0A8V1A9G1
    Conserved Domains (1) summary
    cd00086
    Location:134 → 192
    homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052543.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    8781747..8791269 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040646095.2 → XP_040502029.1  homeobox protein ANF-1 isoform X1

    UniProtKB/Swiss-Prot
    P79775
    UniProtKB/TrEMBL
    A0A8V1A9G1
    Related
    ENSGALP00010039866.1, ENSGALT00010065575.1
    Conserved Domains (1) summary
    cd00086
    Location:134 → 192
    homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.

  2. XM_046899813.1 → XP_046755769.1  homeobox protein ANF-1 isoform X1

    UniProtKB/Swiss-Prot
    P79775
    UniProtKB/TrEMBL
    A0A8V1A9G1

  3. XM_040646097.2 → XP_040502031.1  homeobox protein ANF-1 isoform X1

    UniProtKB/Swiss-Prot
    P79775
    UniProtKB/TrEMBL
    A0A8V1A9G1
    Conserved Domains (1) summary
    cd00086
    Location:134 → 192
    homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.

  4. XM_040646096.2 → XP_040502030.1  homeobox protein ANF-1 isoform X1

    UniProtKB/Swiss-Prot
    P79775
    UniProtKB/TrEMBL
    A0A8V1A9G1
    Conserved Domains (1) summary
    cd00086
    Location:134 → 192
    homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.

  5. XM_046899810.1 → XP_046755766.1  homeobox protein ANF-1 isoform X1

    UniProtKB/Swiss-Prot
    P79775
    UniProtKB/TrEMBL
    A0A8V1A9G1

  6. XM_046899809.1 → XP_046755765.1  homeobox protein ANF-1 isoform X1

    UniProtKB/Swiss-Prot
    P79775
    UniProtKB/TrEMBL
    A0A8V1A9G1

  7. XM_046899814.1 → XP_046755770.1  homeobox protein ANF-1 isoform X1

    UniProtKB/Swiss-Prot
    P79775
    UniProtKB/TrEMBL
    A0A8V1A9G1

  8. XM_046899812.1 → XP_046755768.1  homeobox protein ANF-1 isoform X1

    UniProtKB/Swiss-Prot
    P79775
    UniProtKB/TrEMBL
    A0A8V1A9G1

  9. XM_046899811.1 → XP_046755767.1  homeobox protein ANF-1 isoform X1

    UniProtKB/Swiss-Prot
    P79775
    UniProtKB/TrEMBL
    A0A8V1A9G1

  10. XM_015292965.4 → XP_015148451.2  homeobox protein ANF-1 isoform X2

    Conserved Domains (1) summary
    cd00086
    Location:113 → 171
    homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.

  11. XM_046899815.1 → XP_046755771.1  homeobox protein ANF-1 isoform X2

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052584.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    8809327..8818539 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046926049.1 → XP_046782005.1  homeobox protein ANF-1 isoform X1

    UniProtKB/Swiss-Prot
    P79775
    UniProtKB/TrEMBL
    A0A8V1A9G1

  2. XM_046926056.1 → XP_046782012.1  homeobox protein ANF-1 isoform X2

  3. XM_046926054.1 → XP_046782010.1  homeobox protein ANF-1 isoform X1

    UniProtKB/Swiss-Prot
    P79775
    UniProtKB/TrEMBL
    A0A8V1A9G1

  4. XM_046926051.1 → XP_046782007.1  homeobox protein ANF-1 isoform X1

    UniProtKB/Swiss-Prot
    P79775
    UniProtKB/TrEMBL
    A0A8V1A9G1

  5. XM_046926050.1 → XP_046782006.1  homeobox protein ANF-1 isoform X1

    UniProtKB/Swiss-Prot
    P79775
    UniProtKB/TrEMBL
    A0A8V1A9G1

  6. XM_046926048.1 → XP_046782004.1  homeobox protein ANF-1 isoform X1

    UniProtKB/Swiss-Prot
    P79775
    UniProtKB/TrEMBL
    A0A8V1A9G1

  7. XM_046926057.1 → XP_046782013.1  homeobox protein ANF-1 isoform X2

  8. XM_046926047.1 → XP_046782003.1  homeobox protein ANF-1 isoform X1

    UniProtKB/Swiss-Prot
    P79775
    UniProtKB/TrEMBL
    A0A8V1A9G1

  9. XM_046926055.1 → XP_046782011.1  homeobox protein ANF-1 isoform X1

    UniProtKB/Swiss-Prot
    P79775
    UniProtKB/TrEMBL
    A0A8V1A9G1

  10. XM_046926058.1 → XP_046782014.1  homeobox protein ANF-1 isoform X2

  11. XM_046926053.1 → XP_046782009.1  homeobox protein ANF-1 isoform X1

    UniProtKB/Swiss-Prot
    P79775
    UniProtKB/TrEMBL
    A0A8V1A9G1

  12. XM_046926052.1 → XP_046782008.1  homeobox protein ANF-1 isoform X1

    UniProtKB/Swiss-Prot
    P79775
    UniProtKB/TrEMBL
    A0A8V1A9G1
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P79775.2 GenPept UniProtKB/Swiss-Prot:P79775

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