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DDX5 DEAD-box helicase 5 [ Gallus gallus (chicken) ]

Gene ID: 395629, updated on 17-Aug-2024

Summary

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Symbol
DDX5provided by CGNC
Full Name
DEAD-box helicase 5provided by CGNC
Primary source
CGNC:49411
See related
Ensembl:ENSGALG00010029634
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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See DDX5 in Genome Data Viewer
Location:
chromosome: 18
Exon count:
13
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 18 NC_052549.1 (7518835..7526313, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 18 NC_052590.1 (7113746..7121213, complement)

Chromosome 18 - NC_052549.1Genomic Context describing neighboring genes Neighboring gene testis expressed 2 Neighboring gene platelet and endothelial cell adhesion molecule 1 Neighboring gene mast cell immunoglobulin like receptor 1 Neighboring gene DNA polymerase gamma 2, accessory subunit Neighboring gene microRNA 3064 Neighboring gene centrosomal protein 95 Neighboring gene SMAD specific E3 ubiquitin protein ligase 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A chicken embryo protein related to the mammalian DEAD box protein p68 is tightly associated with the highly purified protein-RNA complex of 5-MeC-DNA glycosylase. Jost JP, et al. Nucleic Acids Res, 1999 Aug 15. PMID 10454630, Free PMC Article
  2. DEAD/DEAH-box helicase 5 is hijacked by an avian oncogenic herpesvirus to inhibit interferon beta production and promote viral replication. Xu J, et al. Dev Comp Immunol, 2021 Jun. PMID 33609615

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. DEAD/DEAH-box helicase 5 is hijacked by an avian oncogenic herpesvirus to inhibit interferon beta production and promote viral replication.
    Title: DEAD/DEAH-box helicase 5 is hijacked by an avian oncogenic herpesvirus to inhibit interferon beta production and promote viral replication.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA helicase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in alternative mRNA splicing, via spliceosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
probable ATP-dependent RNA helicase DDX5
Names
DEAD (Asp-Glu-Ala-Asp) box helicase 5
DEAD (Asp-Glu-Ala-Asp) box polypeptide 5
DEAD-box RNA helicase
NP_990158.1
XP_015135357.1
XP_046785210.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_204827.2 → NP_990158.1  probable ATP-dependent RNA helicase DDX5

    See identical proteins and their annotated locations for NP_990158.1

    Status: PROVISIONAL

    Source sequence(s)
    JAENSK010000317
    UniProtKB/TrEMBL
    A0A8V1APK2, F1NM08, Q9W744
    Related
    ENSGALP00010044342.1, ENSGALT00010071652.1
    Conserved Domains (2) summary
    PTZ00110
    Location:9 → 462
    PTZ00110; helicase; Provisional
    pfam08061
    Location:534 → 564
    P68HR; P68HR (NUC004) repeat

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052549.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    7518835..7526313 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015279871.4 → XP_015135357.1  probable ATP-dependent RNA helicase DDX5 isoform X1

    UniProtKB/TrEMBL
    A0A3S5ZPN3, A0A8V1APK2
    Related
    ENSGALP00010044343.1, ENSGALT00010071653.1
    Conserved Domains (2) summary
    PTZ00110
    Location:2 → 470
    PTZ00110; helicase; Provisional
    pfam08061
    Location:542 → 572
    P68HR; P68HR (NUC004) repeat

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052590.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    7113746..7121213 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046929254.1 → XP_046785210.1  probable ATP-dependent RNA helicase DDX5 isoform X1

    UniProtKB/TrEMBL
    A0A3S5ZPN3, A0A8V1APK2
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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