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MEIS1 Meis homeobox 1 [ Gallus gallus (chicken) ]

Gene ID: 395589, updated on 10-Oct-2024

Summary

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Official Symbol
MEIS1provided by CGNC
Official Full Name
Meis homeobox 1provided by CGNC
Primary source
CGNC:49389
See related
Ensembl:ENSGALG00010017708
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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See MEIS1 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
13
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 3 NC_052534.1 (10658088..10750412)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 3 NC_052575.1 (10603370..10697098)

Chromosome 3 - NC_052534.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121113161 Neighboring gene sprouty related EVH1 domain containing 2 Neighboring gene microRNA 6711 Neighboring gene uncharacterized LOC107052010 Neighboring gene uncharacterized LOC101751026 Neighboring gene uncharacterized LOC107052009 Neighboring gene uncharacterized LOC421268 Neighboring gene Ewing tumor associated antigen 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Distinct and redundant expression and transcriptional diversity of MEIS gene paralogs during chicken development. Sánchez-Guardado LÓ, et al. Dev Dyn, 2011 Jun. PMID 21465619
  2. Meis gene expression patterns in the developing chicken inner ear. Sánchez-Guardado LÓ, et al. J Comp Neurol, 2011 Jan 1. PMID 21120931
  3. Conserved regulation of proximodistal limb axis development by Meis1/Hth. Mercader N, et al. Nature, 1999 Nov 25. PMID 10586884
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Detailed analysis of chick Meis1/2 expression patterns during early embryogenesis and organogenesis.
    Title: Distinct and redundant expression and transcriptional diversity of MEIS gene paralogs during chicken development.
  2. Our results suggest a possible role of Meis assigning regional identity in the morphogenesis, patterning, and specification of the developing inner ear.
    Title: Meis gene expression patterns in the developing chicken inner ear.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription activator activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in angiogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in animal organ morphogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in brain development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in embryonic pattern specification IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in eye development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in hemopoiesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
homeobox protein Meis1
Names
myeloid ecotropic viral insertion site-1a protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001139477.1 → NP_001132949.1  homeobox protein Meis1

    See identical proteins and their annotated locations for NP_001132949.1

    Status: PROVISIONAL

    Source sequence(s)
    FJ265709
    UniProtKB/TrEMBL
    B6Z9R2, Q9PTF1
    Conserved Domains (2) summary
    pfam05920
    Location:290 → 329
    Homeobox_KN; Homeobox KN domain
    pfam16493
    Location:108 → 191
    Meis_PKNOX_N; N-terminal of Homeobox Meis and PKNOX1

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052534.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    10658088..10750412
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015278039.4 → XP_015133525.1  homeobox protein Meis1 isoform X1

    UniProtKB/TrEMBL
    A0A3Q2U0L7, Q9PTF1
    Related
    ENSGALP00010025315.1, ENSGALT00010042825.1
    Conserved Domains (3) summary
    pfam07271
    Location:324 → 455
    Cytadhesin_P30; Cytadhesin P30/P32
    pfam05920
    Location:290 → 329
    Homeobox_KN; Homeobox KN domain
    pfam16493
    Location:108 → 192
    Meis_PKNOX_N; N-terminal of Homeobox Meis and PKNOX1

  2. XM_015278041.4 → XP_015133527.1  homeobox protein Meis1 isoform X3

    UniProtKB/TrEMBL
    Q9PTF1
    Related
    ENSGALP00010025313.1, ENSGALT00010042823.1
    Conserved Domains (2) summary
    pfam05920
    Location:290 → 329
    Homeobox_KN; Homeobox KN domain
    pfam16493
    Location:108 → 192
    Meis_PKNOX_N; N-terminal of Homeobox Meis and PKNOX1

  3. XM_046938427.1 → XP_046794383.1  homeobox protein Meis1 isoform X2

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052575.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    10603370..10697098
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046913004.1 → XP_046768960.1  homeobox protein Meis1 isoform X1

    UniProtKB/TrEMBL
    A0A3Q2U0L7

  2. XM_046913006.1 → XP_046768962.1  homeobox protein Meis1 isoform X3

  3. XM_046913005.1 → XP_046768961.1  homeobox protein Meis1 isoform X2

Nucleotide Protein Strain
Heading Accession and Version

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Research Materials