COL2A1 collagen type II alpha 1 chain [Gallus gallus (chicken)] - Gene

Summary

Official Symbol: COL2A1provided by CGNC
Official Full Name: collagen type II alpha 1 chainprovided by CGNC
Primary source: CGNC:49161
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Annotation information: Annotation category: suggests misassembly; Annotation category: partial on reference assembly
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 34

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	34	NC_052565.1 (1138569..1141506, complement)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	34	NC_052606.1 (1082265..1100836, complement)

Chromosome 34 - NC_052565.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

We examined the molecular details by which lubricin interacts with type II collagen and how binding is related to boundary lubrication and adhesive interactions; and whether collagen structure can affect lubricin adsorption.
Title: Interaction of lubricin with type II collagen surfaces: adsorption, friction, and normal forces.
the structural organization, evolutional characters, developmental expression and chromosomal mapping of the gene
Title: Molecular cloning, characterization and localization of chicken type II procollagen gene.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables extracellular matrix structural constituent	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of collagen type II trimer	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: collagen alpha-1(II) chain

Names: alpha 1 type II procollagen; alpha 1 type IIA collagen; alpha-1 type II collagen; collagen, type II, alpha 1 (primary osteoarthritis, spondyloepiphyseal dysplasia, congenital); procollagen alpha 1(II); type II collagen; type II procollagen

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_204426.2 → NP_989757.2 collagen alpha-1(II) chain precursor

Status: VALIDATED

Source sequence(s)

AY046949, JAENSL010000311

Conserved Domains (2) summary

smart00038
Location:1185 → 1420

COLFI; Fibrillar collagens C-terminal domain

PRK07764
Location:233 → 594

PRK07764; DNA polymerase III subunits gamma and tau; Validated

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

NC_052565.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Range

1138569..1141506 complement

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GenBank, FASTA, Sequence Viewer (Graphics)