snai2 snail family transcriptional repressor 2 [Xenopus tropicalis (tropical clawed frog)] - Gene

Summary

Official Symbol: snai2provided by Xenbase
Official Full Name: snail family transcriptional repressor 2provided by Xenbase
Primary source: Xenbase:XB-GENE-487371
See related: Ensembl:ENSXETG00000024006 AllianceGenome:Xenbase:XB-GENE-487371
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus tropicalis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as: slug; ws2d; xSlu; xslug; Snail2; slugh1; XSnail2; snai2-a; snai2-b
Summary: Predicted to enable DNA binding activity and metal ion binding activity. Predicted to be located in nucleus. Is expressed in ectoderm and nervous system. Human ortholog(s) of this gene implicated in piebaldism. Orthologous to human SNAI2 (snail family transcriptional repressor 2). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 6

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
104	current	UCB_Xtro_10.0 (GCF_000004195.4)	6	NC_030682.2 (113563355..113566860, complement)
103	previous assembly	Xenopus_tropicalis_v9.1 (GCF_000004195.3)	6	NC_030682.1 (98673930..98677440, complement)

Chromosome 6 - NC_030682.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

A new transgenic reporter line reveals Wnt-dependent Snai2 re-expression and cranial neural crest differentiation in Xenopus.
Title: A new transgenic reporter line reveals Wnt-dependent Snai2 re-expression and cranial neural crest differentiation in Xenopus.

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

Go to the top of the page Help

Preferred Names: zinc finger protein SNAI2

Names: snail family zinc finger 2; snail homolog 2; zinc finger transcription factor slug

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_204093.1 → NP_989424.1 zinc finger protein SNAI2

See identical proteins and their annotated locations for NP_989424.1

Status: PROVISIONAL

Source sequence(s)

AF368039

UniProtKB/TrEMBL

F7EKS2, Q6DJ09, Q90VW4

Related

ENSXETP00000051787.2, ENSXETT00000051787.4

Conserved Domains (5) summary

sd00017
Location:185 → 205

ZF_C2H2; C2H2 Zn finger [structural motif]

sd00019
Location:128 → 148

ZF_C2H2; C2H2 Zn finger [structural motif]

pfam00096
Location:211 → 233

zf-C2H2; Zinc finger, C2H2 type

pfam13465
Location:198 → 221

zf-H2C2_2; Zinc-finger double domain

pfam15961
Location:82 → 160

DUF4764; Domain of unknown function (DUF4764)