U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

myc MYC proto-oncogene, bHLH transcription factor [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 395024, updated on 4-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
mycprovided by Xenbase
Official Full Name
MYC proto-oncogene, bHLH transcription factorprovided by Xenbase
Primary source
Xenbase:XB-GENE-6052814
See related
Ensembl:ENSXETG00000025372 AllianceGenome:Xenbase:XB-GENE-6052814
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as
cmyc; Xcmyc; c-myc; myc-a; myc-b; X-cmyc
Summary
Predicted to enable DNA binding activity; DNA-binding transcription factor activity; and protein dimerization activity. Predicted to act upstream of or within regulation of DNA-templated transcription. Predicted to be located in nucleus. Is expressed in ectoderm and visual system. Human ortholog(s) of this gene implicated in several diseases, including angiosarcoma; carcinoma (multiple); demyelinating disease; hematologic cancer (multiple); and prostate cancer (multiple). Orthologous to human MYC (MYC proto-oncogene, bHLH transcription factor). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See myc in Genome Data Viewer
Location:
chromosome: 6
Exon count:
4
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 6 NC_030682.2 (141192685..141203950)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 6 NC_030682.1 (128990797..129003213, complement)

Chromosome 6 - NC_030682.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC116411606 Neighboring gene LRAT domain containing 2 Neighboring gene uncharacterized LOC100487686 Neighboring gene U2 spliceosomal RNA

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Clone Names

  • MGC76254

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
  
enables protein dimerization activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
myc proto-oncogene protein
Names
v-myc avian myelocytomatosis viral oncogene homolog

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_204059.1 → NP_989390.1  myc proto-oncogene protein

    See identical proteins and their annotated locations for NP_989390.1

    Status: PROVISIONAL

    Source sequence(s)
    BC064880
    UniProtKB/TrEMBL
    A0A803KKD3, F6XTZ4, Q6P1T1
    Related
    ENSXETP00000105231.1, ENSXETT00000113222.1
    Conserved Domains (2) summary
    pfam01056
    Location:6 → 324
    Myc_N; Myc amino-terminal region
    cd11458
    Location:330 → 413
    bHLHzip_c-Myc; basic Helix-Loop-Helix-zipper (bHLHzip) domain found in c-Myc and similar proteins

RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030682.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    141192685..141203950
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012964474.3 → XP_012819928.1  myc proto-oncogene protein isoform X1

    See identical proteins and their annotated locations for XP_012819928.1

    UniProtKB/TrEMBL
    A0A803KKD3, F6XTZ4, Q6P1T1
    Conserved Domains (2) summary
    pfam01056
    Location:6 → 324
    Myc_N; Myc amino-terminal region
    cd11458
    Location:330 → 413
    bHLHzip_c-Myc; basic Helix-Loop-Helix-zipper (bHLHzip) domain found in c-Myc and similar proteins
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.