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camk1gb calcium/calmodulin-dependent protein kinase IGb [ Danio rerio (zebrafish) ]

Gene ID: 393802, updated on 2-Nov-2024

Summary

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Official Symbol
camk1gbprovided by ZNC
Official Full Name
calcium/calmodulin-dependent protein kinase IGbprovided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-1694
See related
Ensembl:ENSDARG00000008788 AllianceGenome:ZFIN:ZDB-GENE-040426-1694
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fk61c03; zgc:73155; wu:fk61c03
Summary
Predicted to enable calcium/calmodulin-dependent protein kinase activity and calmodulin binding activity. Acts upstream of or within locomotor rhythm. Predicted to be active in cytoplasm. Is expressed in diencephalon; sensory system; and yolk syncytial layer. Orthologous to human CAMK1G (calcium/calmodulin dependent protein kinase IG). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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See camk1gb in Genome Data Viewer
Location:
chromosome: 23
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 23 NC_007134.7 (39558508..39594730)
105 previous assembly GRCz10 (GCF_000002035.5) 23 NC_007134.6 (39661413..39704990)

Chromosome 23 - NC_007134.7Genomic Context describing neighboring genes Neighboring gene v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog Neighboring gene uncharacterized LOC137489146 Neighboring gene microtubule associated monooxygenase, calponin and LIM domain containing 1 Neighboring gene G0/G1 switch 2 Neighboring gene OTU deubiquitinase 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Whole-genome expression profile in zebrafish embryos after chronic exposure to morphine: identification of new genes associated with neuronal function and mu opioid receptor expression. Herrero-Turrión MJ, et al. BMC Genomics, 2014 Oct 8. PMID 25294025, Free PMC Article
  2. Systematic identification of rhythmic genes reveals camk1gb as a new element in the circadian clockwork. Tovin A, et al. PLoS Genet, 2012. PMID 23284293, Free PMC Article
  3. Corticotropin-releasing hormone family evolution: five ancestral genes remain in some lineages. Cardoso JC, et al. J Mol Endocrinol, 2016 Jul. PMID 27220618
  4. The vertebrate ancestral repertoire of visual opsins, transducin alpha subunits and oxytocin/vasopressin receptors was established by duplication of their shared genomic region in the two rounds of early vertebrate genome duplications. Lagman D, et al. BMC Evol Biol, 2013 Nov 2. PMID 24180662, Free PMC Article
  5. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. knockdown of camk1gb disrupts locomotor activity in the whole larva, even though it is predominantly expressed within the pineal gland.
    Title: Systematic identification of rhythmic genes reveals camk1gb as a new element in the circadian clockwork.
Submit: New GeneRIF Correction

General gene information

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Markers

Homology

Clone Names

  • MGC73155

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables calcium/calmodulin-dependent protein kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables calcium/calmodulin-dependent protein kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables calmodulin binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within locomotor rhythm IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within phosphorylation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within protein phosphorylation IEA
Inferred from Electronic Annotation
more info
  
involved_in signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
calcium/calmodulin-dependent protein kinase IGb
NP_957123.1
XP_005174189.1
XP_021325441.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_200829.1 → NP_957123.1  calcium/calmodulin-dependent protein kinase IGb

    See identical proteins and their annotated locations for NP_957123.1

    Status: PROVISIONAL

    Source sequence(s)
    BC060911
    UniProtKB/TrEMBL
    Q6P965
    Related
    ENSDARP00000011264.7, ENSDART00000017902.8
    Conserved Domains (2) summary
    smart00220
    Location:21 → 274
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cl21453
    Location:17 → 300
    PKc_like; Protein Kinases, catalytic domain

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007134.7 Reference GRCz11 Primary Assembly

    Range
    39558508..39594730
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021469766.2 → XP_021325441.1  calcium/calmodulin-dependent protein kinase IGb isoform X1

    UniProtKB/TrEMBL
    A0A8M9PSZ5
    Conserved Domains (1) summary
    cl21453
    Location:70 → 353
    PKc_like; Protein Kinases, catalytic domain

  2. XM_005174132.5 → XP_005174189.1  calcium/calmodulin-dependent protein kinase IGb isoform X2

    UniProtKB/TrEMBL
    A0A8M2BLE1, F1QB46
    Conserved Domains (2) summary
    smart00220
    Location:21 → 274
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cl21453
    Location:17 → 300
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein Strain
Heading Accession and Version

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