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LRRC10B leucine rich repeat containing 10B [ Homo sapiens (human) ]

Gene ID: 390205, updated on 17-Sep-2024

Summary

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Official Symbol
LRRC10Bprovided by HGNC
Official Full Name
leucine rich repeat containing 10Bprovided by HGNC
Primary source
HGNC:HGNC:37215
See related
Ensembl:ENSG00000204950 AllianceGenome:HGNC:37215
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Orthologs
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Genomic context

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See LRRC10B in Genome Data Viewer
Location:
11q12.2
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (61508749..61511018)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (61497629..61499898)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (61276221..61278490)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105369329 Neighboring gene MPRA-validated peak1286 silencer Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:61280313-61280926 Neighboring gene microRNA 4488 Neighboring gene synaptotagmin 7 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:61297435-61297934 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:61301414-61302353 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:61302354-61303292 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3394 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3395 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3396 Neighboring gene uncharacterized LOC105369331 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:61354237-61354816 Neighboring gene uncharacterized LOC101927495 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:61355975-61356553 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:61366831-61367498 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:61368167-61368834

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. LRRC10B may be a downstream gene regulated by RPLP0P2
    Title: Low expression lncRNA RPLP0P2 is associated with poor prognosis and decreased cell proliferation and adhesion ability in lung adenocarcinoma.
Submit: New GeneRIF Correction

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

General protein information

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Preferred Names
leucine-rich repeat-containing protein 10B
Names
LRRC10-like protein ENSP00000367315

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001145077.2 → NP_001138549.1  leucine-rich repeat-containing protein 10B

    See identical proteins and their annotated locations for NP_001138549.1

    Status: VALIDATED

    Source sequence(s)
    AP003108, AW137416
    Consensus CDS
    CCDS44621.1
    UniProtKB/Swiss-Prot
    A6NIK2
    Related
    ENSP00000367315.2, ENST00000378075.4
    Conserved Domains (3) summary
    sd00033
    Location:24 → 45
    LRR_RI; leucine-rich repeat [structural motif]
    pfam12799
    Location:90 → 129
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:90 → 148
    LRR_8; Leucine rich repeat

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

    Range
    61508749..61511018
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060935.1 Alternate T2T-CHM13v2.0

    Range
    61497629..61499898
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A6NIK2.2 GenPept UniProtKB/Swiss-Prot:A6NIK2

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
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