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camk2g.S calcium/calmodulin dependent protein kinase (CaM kinase) II gamma S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 380508, updated on 4-Nov-2024

Summary

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Official Symbol
camk2g.S
Official Full Name
calcium/calmodulin dependent protein kinase (CaM kinase) II gamma S homeolog
Primary source
Xenbase:XB-GENE-868549
Locus tag
XELAEV_18037152mg
See related
EnsemblRapid:ENSXLAG00005005015 AllianceGenome:Xenbase:XB-GENE-868549
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
camk2; CamKII; camk2g
Summary
Predicted to enable ATP binding activity; calcium/calmodulin-dependent protein kinase activity; and calmodulin binding activity. Predicted to act upstream of or within protein phosphorylation. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder. Orthologous to human CAMK2G (calcium/calmodulin dependent protein kinase II gamma). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See camk2g.S in Genome Data Viewer
Location:
chromosome: 7S
Exon count:
25
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 7S NC_054384.1 (33900806..34084229, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 7S NC_030737.1 (32293113..32482144, complement)

Chromosome 7S - NC_054384.1Genomic Context describing neighboring genes Neighboring gene traf2 and NCK-interacting protein kinase-like Neighboring gene N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 S homeolog Neighboring gene protein kinase C delta type Neighboring gene neurogenin 3 S homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Cloning and differential expression of new calcium, calmodulin-dependent protein kinase II isoforms in Xenopus laevis oocytes and several adult tissues. Stevens I, et al. J Biochem, 2001 Apr. PMID 11275554
  2. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC52524

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables calcium/calmodulin-dependent protein kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables calmodulin binding IEA
Inferred from Electronic Annotation
more info
  
enables kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within phosphorylation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within protein phosphorylation IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
calcium/calmodulin dependent protein kinase (CaM kinase) II gamma S homeolog
Names
calcium/calmodulin-dependent protein kinase II gamma B variable region
calcium/calmodulin-dependent protein kinase II gamma C variable region
calcium/calmodulin-dependent protein kinase II gamma subunit variable region
camodulin kinase II
NP_001080814.1
XP_018082303.1
XP_018082304.1
XP_018082305.1
XP_018082306.1
XP_018082307.1
XP_018082308.1
XP_018082309.1
XP_018082310.1
XP_018082311.1
XP_018082312.1
XP_018082313.1
XP_018082315.1
XP_018082316.1
XP_018082317.1
XP_018082318.1
XP_018082319.1
XP_018082320.1
XP_018082321.1
XP_018082322.1
XP_018082323.1
XP_018082324.1
XP_018082326.1
XP_041426319.1
XP_041426321.1
XP_041426322.1
XP_041426323.1
XP_041426324.1
XP_041426325.1
XP_041426326.1
XP_041426327.1
XP_041426328.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001087345.1 → NP_001080814.1  calcium/calmodulin dependent protein kinase (CaM kinase) II gamma S homeolog

    See identical proteins and their annotated locations for NP_001080814.1

    Status: PROVISIONAL

    Source sequence(s)
    AF233631
    UniProtKB/TrEMBL
    A0A974CBL3, Q9DG00
    Related
    ENSXLAP00005015217.1, ENSXLAT00005015494.1
    Conserved Domains (3) summary
    smart00220
    Location:14 → 272
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd14086
    Location:12 → 303
    STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
    pfam08332
    Location:432 → 559
    CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054384.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    33900806..34084229 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041570394.1 → XP_041426328.1  calcium/calmodulin dependent protein kinase (CaM kinase) II gamma S homeolog isoform X31

    UniProtKB/TrEMBL
    A0A8J1L9W8, Q9DFZ9
    Conserved Domains (2) summary
    cd14086
    Location:12 → 303
    STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
    pfam08332
    Location:523 → 650
    CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

  2. XM_018226826.2 → XP_018082315.1  calcium/calmodulin dependent protein kinase (CaM kinase) II gamma S homeolog isoform X15

    UniProtKB/TrEMBL
    A0A8J0TDE1, Q9DFZ9

  3. XM_041570388.1 → XP_041426322.1  calcium/calmodulin dependent protein kinase (CaM kinase) II gamma S homeolog isoform X12

    UniProtKB/TrEMBL
    A0A8J1L9X2, Q9DFZ9
    Conserved Domains (2) summary
    cd14086
    Location:12 → 303
    STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
    pfam08332
    Location:436 → 563
    CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

  4. XM_018226817.2 → XP_018082306.1  calcium/calmodulin dependent protein kinase (CaM kinase) II gamma S homeolog isoform X5

    UniProtKB/TrEMBL
    A0A8J0TE25, Q9DFZ9

  5. XM_041570387.1 → XP_041426321.1  calcium/calmodulin dependent protein kinase (CaM kinase) II gamma S homeolog isoform X10

    UniProtKB/TrEMBL
    A0A8J1LA00, Q9DFZ9
    Conserved Domains (2) summary
    cd14086
    Location:12 → 303
    STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
    pfam08332
    Location:441 → 568
    CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

  6. XM_018226816.2 → XP_018082305.1  calcium/calmodulin dependent protein kinase (CaM kinase) II gamma S homeolog isoform X3

    UniProtKB/TrEMBL
    A0A8J0TDD1, Q9DFZ9

  7. XM_018226819.2 → XP_018082308.1  calcium/calmodulin dependent protein kinase (CaM kinase) II gamma S homeolog isoform X7

    UniProtKB/TrEMBL
    A0A8J0T4I3, Q9DFZ9
    Related
    ENSXLAP00005015183.1, ENSXLAT00005015452.1

  8. XM_041570385.1 → XP_041426319.1  calcium/calmodulin dependent protein kinase (CaM kinase) II gamma S homeolog isoform X4

    UniProtKB/TrEMBL
    A0A8J1LBG5, Q9DFZ9
    Conserved Domains (2) summary
    cd14086
    Location:12 → 303
    STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
    pfam08332
    Location:462 → 589
    CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

  9. XM_018226814.2 → XP_018082303.1  calcium/calmodulin dependent protein kinase (CaM kinase) II gamma S homeolog isoform X1

    UniProtKB/TrEMBL
    A0A8J0T4H8, Q9DFZ9

  10. XM_041570390.1 → XP_041426324.1  calcium/calmodulin dependent protein kinase (CaM kinase) II gamma S homeolog isoform X18

    UniProtKB/TrEMBL
    A0A8J1LBH0, Q9DFZ9
    Conserved Domains (2) summary
    cd14086
    Location:12 → 303
    STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
    pfam08332
    Location:415 → 542
    CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

  11. XM_018226822.2 → XP_018082311.1  calcium/calmodulin dependent protein kinase (CaM kinase) II gamma S homeolog isoform X11

    UniProtKB/TrEMBL
    A0A8J0TE31, Q9DFZ9

  12. XM_018226820.2 → XP_018082309.1  calcium/calmodulin dependent protein kinase (CaM kinase) II gamma S homeolog isoform X8

    UniProtKB/TrEMBL
    A0A8J0TCQ7, Q9DFZ9

  13. XM_018226823.2 → XP_018082312.1  calcium/calmodulin dependent protein kinase (CaM kinase) II gamma S homeolog isoform X13

    UniProtKB/TrEMBL
    A0A8J0TAQ4, Q9DFZ9

  14. XM_018226818.2 → XP_018082307.1  calcium/calmodulin dependent protein kinase (CaM kinase) II gamma S homeolog isoform X6

    UniProtKB/TrEMBL
    A0A8J0TAP9, Q9DFZ9
    Related
    ENSXLAP00005015174.1, ENSXLAT00005015441.1

  15. XM_018226815.2 → XP_018082304.1  calcium/calmodulin dependent protein kinase (CaM kinase) II gamma S homeolog isoform X2

    UniProtKB/TrEMBL
    A0A8J0TCQ2, Q9DFZ9
    Related
    ENSXLAP00005015165.1, ENSXLAT00005015425.1

  16. XM_018226830.2 → XP_018082319.1  calcium/calmodulin dependent protein kinase (CaM kinase) II gamma S homeolog isoform X22

    UniProtKB/TrEMBL
    A0A8J0TCR5, Q9DFZ9

  17. XM_018226824.2 → XP_018082313.1  calcium/calmodulin dependent protein kinase (CaM kinase) II gamma S homeolog isoform X14

    UniProtKB/TrEMBL
    A0A8J0T4I9, Q9DFZ9

  18. XM_041570392.1 → XP_041426326.1  calcium/calmodulin dependent protein kinase (CaM kinase) II gamma S homeolog isoform X25

    UniProtKB/TrEMBL
    A0A8J1LA04, Q9DFZ9
    Conserved Domains (2) summary
    cd14086
    Location:12 → 303
    STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
    pfam08332
    Location:394 → 521
    CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

  19. XM_018226837.2 → XP_018082326.1  calcium/calmodulin dependent protein kinase (CaM kinase) II gamma S homeolog isoform X17

    UniProtKB/TrEMBL
    A0A8J0TDF4, A0A974CBL3
    Related
    ENSXLAP00005015209.1, ENSXLAT00005015485.1

  20. XM_041570391.1 → XP_041426325.1  calcium/calmodulin dependent protein kinase (CaM kinase) II gamma S homeolog isoform X23

    UniProtKB/TrEMBL
    A0A8J1LCE7, Q9DFZ9
    Conserved Domains (2) summary
    cd14086
    Location:12 → 303
    STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
    pfam08332
    Location:399 → 526
    CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

  21. XM_041570389.1 → XP_041426323.1  calcium/calmodulin dependent protein kinase (CaM kinase) II gamma S homeolog isoform X16

    UniProtKB/TrEMBL
    A0A8J1L9W2, Q9DFZ9
    Related
    ENSXLAP00005015193.1, ENSXLAT00005015464.1
    Conserved Domains (2) summary
    cd14086
    Location:12 → 303
    STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
    pfam08332
    Location:420 → 547
    CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

  22. XM_018226821.2 → XP_018082310.1  calcium/calmodulin dependent protein kinase (CaM kinase) II gamma S homeolog isoform X9

    UniProtKB/TrEMBL
    A0A8J0TDD6, A0A974CBL3
    Related
    ENSXLAP00005015187.1, ENSXLAT00005015459.1

  23. XM_041570393.1 → XP_041426327.1  calcium/calmodulin dependent protein kinase (CaM kinase) II gamma S homeolog isoform X29

    UniProtKB/TrEMBL
    A0A8J1L9X6, A0A974CCU9
    Conserved Domains (2) summary
    cd14086
    Location:12 → 303
    STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
    pfam08332
    Location:373 → 500
    CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

  24. XM_018226831.2 → XP_018082320.1  calcium/calmodulin dependent protein kinase (CaM kinase) II gamma S homeolog isoform X24

    UniProtKB/TrEMBL
    A0A8J0TDE7, A0A974CCU9
    Related
    ENSXLAP00005015100.1, ENSXLAT00005015341.1

  25. XM_018226834.2 → XP_018082323.1  calcium/calmodulin dependent protein kinase (CaM kinase) II gamma S homeolog isoform X28

    UniProtKB/TrEMBL
    A0A8J0T4K1, Q9DFZ9

  26. XM_018226829.2 → XP_018082318.1  calcium/calmodulin dependent protein kinase (CaM kinase) II gamma S homeolog isoform X21

    UniProtKB/TrEMBL
    A0A8J0T4J6, A0A974CCU9

  27. XM_018226832.2 → XP_018082321.1  calcium/calmodulin dependent protein kinase (CaM kinase) II gamma S homeolog isoform X26

    UniProtKB/TrEMBL
    A0A8J0TE41, Q9DFZ9

  28. XM_018226827.2 → XP_018082316.1  calcium/calmodulin dependent protein kinase (CaM kinase) II gamma S homeolog isoform X19

    UniProtKB/TrEMBL
    A0A8J0TE36, A0A974CBL3

  29. XM_018226828.2 → XP_018082317.1  calcium/calmodulin dependent protein kinase (CaM kinase) II gamma S homeolog isoform X20

    UniProtKB/TrEMBL
    Q9DFZ9, Q9DG01

  30. XM_018226835.2 → XP_018082324.1  calcium/calmodulin dependent protein kinase (CaM kinase) II gamma S homeolog isoform X30

    UniProtKB/TrEMBL
    A0A8J0TCS2, A0A974CCU9

  31. XM_018226833.2 → XP_018082322.1  calcium/calmodulin dependent protein kinase (CaM kinase) II gamma S homeolog isoform X27

    UniProtKB/TrEMBL
    A0A974CCU9, Q801N3
Nucleotide Protein Strain
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