ednra.L endothelin receptor type A L homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: ednra.L
Official Full Name: endothelin receptor type A L homeolog
Primary source: Xenbase:XB-GENE-1007000
Locus tag: XELAEV_18005510mg
See related: EnsemblRapid:ENSXLAG00005003660
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: eta; etar; etax; etra; ednra; ednraa; endo-r; ednra-a; ednra-b
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Genomic context

Location:: chromosome: 1L

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	1L	NC_054371.1 (60956542..61005400, complement)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	1L	NC_030724.1 (50612027..50660895, complement)

Chromosome 1L - NC_054371.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

A new role for ednra signaling during early neural crest specification is reported.
Title: A new role for the Endothelin-1/Endothelin-A receptor signaling during early neural crest specification.
ET receptors in pigment cells of vertebrate species were identified by RT-PCR assays, and the differential expression of the various subtypes in each species was compared by quantitative PCR.
Title: Expression of endothelin receptors in frog, chicken, mouse and human pigment cells.

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables G protein-coupled receptor activity	IEA Inferred from Electronic Annotation more info
enables endothelin receptor activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within G protein-coupled receptor signaling pathway	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within blood circulation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within developmental pigmentation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within endothelin receptor signaling pathway	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within enteric nervous system development	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within regulation of biological quality	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within regulation of blood pressure	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within vasoconstriction	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: endothelin receptor type A L homeolog

Names: Endothelin-1 receptor type A; endothelin receptor type A a

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001087181.1 → NP_001080650.1 endothelin receptor type A L homeolog precursor

See identical proteins and their annotated locations for NP_001080650.1

Status: PROVISIONAL

Source sequence(s)

BC044316

UniProtKB/TrEMBL

A0A974DX06, Q7ZXQ5, Q91548

Related

ENSXLAP00005010888.1, ENSXLAT00005011062.1

Conserved Domains (1) summary

pfam00001
Location:86 → 356

7tm_1; 7 transmembrane receptor (rhodopsin family)

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

NC_054371.1 Reference Xenopus_laevis_v10.1 Primary Assembly

Range

60956542..61005400 complement

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GenBank, FASTA, Sequence Viewer (Graphics)