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ccn1.S cellular communication network factor 1 S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 379598, updated on 4-Nov-2024

Summary

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Official Symbol
ccn1.S
Official Full Name
cellular communication network factor 1 S homeolog
Primary source
Xenbase:XB-GENE-864894
Locus tag
XELAEV_18025039mg
See related
EnsemblRapid:ENSXLAG00005018632 AllianceGenome:Xenbase:XB-GENE-864894
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
cyr61; Xcyr61; cyr61.S
Summary
Predicted to enable growth factor binding activity; heparin binding activity; and integrin binding activity. Predicted to act upstream of or within cell adhesion and signal transduction. Predicted to be located in extracellular matrix and extracellular region. Is expressed in cardiovascular system; musculoskeletal system; and pharyngeal arch. Human ortholog(s) of this gene implicated in high grade glioma. Orthologous to human CCN1 (cellular communication network factor 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See ccn1.S in Genome Data Viewer
Location:
chromosome: 4S
Exon count:
5
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 4S NC_054378.1 (57980405..57983266, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 4S NC_030731.1 (51794639..51797543, complement)

Chromosome 4S - NC_054378.1Genomic Context describing neighboring genes Neighboring gene histamine H3 receptor Neighboring gene zinc finger, HIT-type containing 6 S homeolog Neighboring gene dimethylarginine dimethylaminohydrolase 1 S homeolog Neighboring gene BCL10, immune signaling adaptor S homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Xenopus Cyr61 regulates gastrulation movements and modulates Wnt signalling. Latinkic BV, et al. Development, 2003 Jun. PMID 12702657
  2. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC64237

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables growth factor binding IEA
Inferred from Electronic Annotation
more info
  
enables heparin binding IEA
Inferred from Electronic Annotation
more info
  
enables integrin binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within cell adhesion IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within signal transduction IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in extracellular matrix IEA
Inferred from Electronic Annotation
more info
  
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
cellular communication network factor 1 S homeolog
Names
cysteine rich angiogenic inducer 61 S homeolog
secreted cysteine-rich protein cyr61

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001086439.1 → NP_001079908.1  cellular communication network factor 1 S homeolog precursor

    See identical proteins and their annotated locations for NP_001079908.1

    Status: PROVISIONAL

    Source sequence(s)
    BC056838
    UniProtKB/TrEMBL
    A0A974CZX4, Q98TX5
    Related
    ENSXLAP00005055074.1, ENSXLAT00005056262.1
    Conserved Domains (4) summary
    smart00209
    Location:227 → 267
    TSP1; Thrombospondin type 1 repeats
    smart00214
    Location:100 → 159
    VWC; von Willebrand factor (vWF) type C domain
    pfam00219
    Location:26 → 78
    IGFBP; Insulin-like growth factor binding protein
    cl21545
    Location:289 → 371
    GHB_like; Glycoprotein hormone beta chain homologues

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054378.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    57980405..57983266 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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