rxra.L retinoid X receptor alpha L homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: rxra.L
Official Full Name: retinoid X receptor alpha L homeolog
Primary source: Xenbase:XB-GENE-865207
Locus tag: XELAEV_18038331mg
See related: EnsemblRapid:ENSXLAG00005020216 AllianceGenome:Xenbase:XB-GENE-865207
Gene type: protein coding
RefSeq status: MODEL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: rxra; nr2b1; xrxra; rxra-A; rxra.S; RXRalpha; xRXR alpha
Summary: Enables nuclear thyroid hormone receptor binding activity and protein heterodimerization activity. Predicted to act upstream of or within several processes, including negative regulation of transcription by RNA polymerase II; response to retinoic acid; and retinoic acid receptor signaling pathway. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in pancreatic cancer. Orthologous to human RXRA (retinoid X receptor alpha). [provided by Alliance of Genome Resources, Nov 2024]
NEW: Try the new Gene table
Try the new Transcript table

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	8L	NC_054385.1 (5384079..5496800, complement)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	8L	NC_030738.1 (5254820..5369591, complement)

Chromosome 8L - NC_054385.1 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables nuclear receptor activity	IEA Inferred from Electronic Annotation more info
enables nuclear steroid receptor activity	IEA Inferred from Electronic Annotation more info
enables nuclear thyroid hormone receptor binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein heterodimerization activity	IPI Inferred from Physical Interaction more info	PubMed
enables retinoic acid-responsive element binding	IEA Inferred from Electronic Annotation more info
enables sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info
enables zinc ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within cell differentiation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within negative regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within regulation of DNA-templated transcription	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within response to retinoic acid	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within retinoic acid receptor signaling pathway	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info

Names: Nuclear receptor subfamily 2 group B member 1; Retinoic acid receptor RXR-alpha; retinoid X receptor alpha S homeolog; retinoid X receptor, alpha