htr7l.S 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled like S homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: htr7l.S
Official Full Name: 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled like S homeolog
Primary source: Xenbase:XB-GENE-5959536
Locus tag: XELAEV_18008783mg
See related: EnsemblRapid:ENSXLAG00005000757 AllianceGenome:Xenbase:XB-GENE-5959536
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: 5HT7; htr7; htr7c; htr7-A
Summary: Predicted to enable G protein-coupled serotonin receptor activity. Predicted to act upstream of or within adenylate cyclase-activating serotonin receptor signaling pathway. Predicted to be located in dendrite. Predicted to be active in plasma membrane. Is expressed in endoderm and mesoderm. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: chromosome: 1S

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	1S	NC_054372.1 (4961337..4997264, complement)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	1S	NC_030725.1 (4832225..4867575, complement)

Chromosome 1S - NC_054372.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables G protein-coupled receptor activity	IEA Inferred from Electronic Annotation more info
enables G protein-coupled serotonin receptor activity	IEA Inferred from Electronic Annotation more info
enables G protein-coupled serotonin receptor activity	ISS Inferred from Sequence or Structural Similarity more info
enables neurotransmitter receptor activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within G protein-coupled receptor signaling pathway	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within adenylate cyclase-activating serotonin receptor signaling pathway	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within chemical synaptic transmission	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within circadian rhythm	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within smooth muscle contraction	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within vasoconstriction	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in dendrite	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info
is_active_in plasma membrane	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: 5-hydroxytryptamine receptor 7

Names: 5-HT-7; 5-HT7; 5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled); hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled); serotonin receptor 7

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001085784.1 → NP_001079253.1 5-hydroxytryptamine receptor 7

See identical proteins and their annotated locations for NP_001079253.1

Status: PROVISIONAL

Source sequence(s)

U10161

UniProtKB/Swiss-Prot

Q91559

Conserved Domains (2) summary

pfam00001
Location:87 → 380

7tm_1; 7 transmembrane receptor (rhodopsin family)

cl21561
Location:83 → 204

7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

NC_054372.1 Reference Xenopus_laevis_v10.1 Primary Assembly

Range

4961337..4997264 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_018232576.2 → XP_018088065.1 5-hydroxytryptamine receptor 7 isoform X1

UniProtKB/TrEMBL

A0A1L8HKF3, A0A974DRI5

Related

ENSXLAP00005002237.1, ENSXLAT00005002283.1

Conserved Domains (1) summary

cd15329
Location:71 → 391

7tmA_5-HT7; serotonin receptor subtype 7, member of the class A family of seven-transmembrane G protein-coupled receptors
XM_041572676.1 → XP_041428610.1 5-hydroxytryptamine receptor 7 isoform X1

UniProtKB/TrEMBL

A0A1L8HKF3, A0A974DRI5

Conserved Domains (1) summary

cd15329
Location:71 → 391

7tmA_5-HT7; serotonin receptor subtype 7, member of the class A family of seven-transmembrane G protein-coupled receptors