FOXO1 forkhead box O1 [Gallus gallus (chicken)] - Gene

Summary

Official Symbol: FOXO1provided by CGNC
Official Full Name: forkhead box O1provided by CGNC
Primary source: CGNC:49093
See related: Ensembl:ENSGALG00010002646
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as: FOXO1A
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 1

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	1	NC_052532.1 (170460551..170524492)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	1	NC_052573.1 (170532030..170595953)

Chromosome 1 - NC_052532.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

These findings have provided a novel mechanism whereby miR-16 represses Bcl2 and FOXO1 expression to maintain myoblast growth and skeletal muscle mass.
Title: miR-16 controls myoblast proliferation and apoptosis through directly suppressing Bcl2 and FOXO1 activities.
refeeding stimulates phosphorylation of Akt/FOXO, resulting in a decrease in atrogin-1 expression in skeletal muscle of chicks
Title: Effects of fasting and refeeding on expression of atrogin-1 and Akt/FOXO signaling pathway in skeletal muscle of chicks.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IEA Inferred from Electronic Annotation more info	PubMed
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in insulin receptor signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: forkhead box protein O1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_204328.2 → NP_989659.2 forkhead box protein O1

Status: VALIDATED

Source sequence(s)

JAENSK010000027

UniProtKB/TrEMBL

A0A8V0XGP1, Q9W7F9

Related

ENSGALP00010003831.1, ENSGALT00010006140.1

Conserved Domains (1) summary

smart00339
Location:152 → 234

FH; FORKHEAD