FLT1 fms related receptor tyrosine kinase 1 [Gallus gallus (chicken)] - Gene

Summary

Symbol: FLT1provided by CGNC
Full Name: fms related receptor tyrosine kinase 1provided by CGNC
Primary source: CGNC:49041
See related: Ensembl:ENSGALG00010005282
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 1

Exon count:: 30

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	1	NC_052532.1 (175670192..175773584)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	1	NC_052573.1 (175753315..175856675)

Chromosome 1 - NC_052532.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables vascular endothelial growth factor receptor activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in cell migration	IEA Inferred from Electronic Annotation more info	PubMed
involved_in multicellular organism development	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of angiogenesis	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of kinase activity	IEA Inferred from Electronic Annotation more info	PubMed
involved_in protein phosphorylation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in vascular endothelial growth factor receptor signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed
part_of receptor complex	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

Go to the top of the page Help

Preferred Names: vascular endothelial growth factor receptor 1

Names: VEGFR-1; fms related tyrosine kinase 1; vascular endothelial growth factor/vascular permeability factor receptor

NP_989583.2

EC 2.7.10.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_204252.2 → NP_989583.2 vascular endothelial growth factor receptor 1 precursor

Status: VALIDATED

Source sequence(s)

JAENSK010000027

UniProtKB/Swiss-Prot

Q8QHL2, Q8QHL3

Related

ENSGALP00010007112.1, ENSGALT00010012548.1

Conserved Domains (5) summary

smart00408
Location:350 → 400

IGc2; Immunoglobulin C-2 Type

smart00409
Location:659 → 738

IG; Immunoglobulin

smart00410
Location:37 → 106

IG_like; Immunoglobulin like

cd00096
Location:349 → 353

Ig; Ig strand B [structural motif]

cl21453
Location:811 → 1150

PKc_like; Protein Kinases, catalytic domain