MYH1B myosin, heavy chain 1B, skeletal muscle (similar to human myosin, heavy chain 1, skeletal muscle, adult) [Gallus gallus (chicken)] - Gene

Summary

Official Symbol: MYH1Bprovided by CGNC
Official Full Name: myosin, heavy chain 1B, skeletal muscle (similar to human myosin, heavy chain 1, skeletal muscle, adult)provided by CGNC
Primary source: CGNC:49031
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as: MYH3
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Genomic context

Location:: chromosome: 18

Exon count:: 40

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	18	NC_052549.1 (1119963..1138129, complement)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	18	NC_052590.1 (688572..706876, complement)

Chromosome 18 - NC_052549.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

EMX2 activates MyHC2 gene expression in embryonic muscle fibers.
Title: EMX2 activates slow myosin heavy chain 2 gene expression in embryonic muscle fibers.
Results indicate that slow muscle fibers can be induced by electrical stimulation to express the slow MyHC2 gene and that fast muscle fibers are refractory to stimulation-induced slow MyHC2 gene expression.
Title: Muscle fiber type specific induction of slow myosin heavy chain 2 gene expression by electrical stimulation.
urea-induced inactivation of the enzyme is caused by partial unfolding of the myosin catalytic domain
Title: Betaine protects urea-induced denaturation of myosin subfragment-1.
the highly conserved Asp-137 destabilizes the middle of Tm, resulting in a more flexible region that is important for the cooperative activation of the thin filament by myosin
Title: Conserved Asp-137 imparts flexibility to tropomyosin and affects function.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables actin filament binding	IEA Inferred from Electronic Annotation more info	PubMed
enables cytoskeletal motor activity	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of myosin complex	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: myosin, heavy chain 1B, skeletal muscle

Names: myosin heavy chain 3; myosin heavy chain, fast skeletal muscle, embryonic; myosin-1B; myosin-3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_204228.4 → NP_989559.3 myosin, heavy chain 1B, skeletal muscle

Status: VALIDATED

Source sequence(s)

JAENSK010000315

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

NC_052549.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Range

1119963..1138129 complement

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GenBank, FASTA, Sequence Viewer (Graphics)