U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

AHR1A aryl hydrocarbon receptor 1 alpha [ Gallus gallus (chicken) ]

Gene ID: 373907, updated on 17-Aug-2024

Summary

Go to the top of the page Help
Official Symbol
AHR1Aprovided by CGNC
Official Full Name
aryl hydrocarbon receptor 1 alphaprovided by CGNC
Primary source
CGNC:8232
See related
Ensembl:ENSGALG00010004433
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
AHR
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See AHR1A in Genome Data Viewer
Location:
chromosome: 2
Exon count:
24
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 2 NC_052533.1 (28471720..28722202)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 2 NC_052574.1 (28504992..28755558)

Chromosome 2 - NC_052533.1Genomic Context describing neighboring genes Neighboring gene basic leucine zipper and W2 domains 2 Neighboring gene tetraspanin 13 Neighboring gene anterior gradient 2, protein disulphide isomerase family member Neighboring gene anterior gradient 3, protein disulphide isomerase family member Neighboring gene uncharacterized LOC121109866 Neighboring gene sorting nexin 13 Neighboring gene uncharacterized LOC107052559

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Evaluation of the Aryl Hydrocarbon Receptor Response in LMH 3D Spheroids. Sharin T, et al. Environ Toxicol Chem, 2020 Sep. PMID 32452045
  2. The molecular basis for differential dioxin sensitivity in birds: role of the aryl hydrocarbon receptor. Karchner SI, et al. Proc Natl Acad Sci U S A, 2006 Apr 18. PMID 16606854, Free PMC Article
  3. Towards molecular understanding of species differences in dioxin sensitivity: initial characterization of Ah receptor cDNAs in birds and an amphibian. Karchner SI, et al. Mar Environ Res, 2000 Jul-Dec. PMID 11460741
  4. Aryl hydrocarbon receptor activation by dioxin targets phosphoenolpyruvate carboxykinase (PEPCK) for ADP-ribosylation via 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-inducible poly(ADP-ribose) polymerase (TiPARP). Diani-Moore S, et al. J Biol Chem, 2013 Jul 26. PMID 23770670, Free PMC Article
  5. Aryl hydrocarbon receptor activation leads to impairment of estrogen-driven chicken vitellogenin promoter activity in LMH cells. Bussmann UA, et al. Comp Biochem Physiol C Toxicol Pharmacol, 2013 Mar. PMID 23103859

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Evaluation of the Aryl Hydrocarbon Receptor Response in LMH 3D Spheroids.
    Title: Evaluation of the Aryl Hydrocarbon Receptor Response in LMH 3D Spheroids.
  2. Data indicate that aryl hydrocarbon receptor (AHR) enhances phosphoenolpyruvate carboxykinase (PEPCK) ADP-ribosylation through TiPARP TiPARP (TCDD-inducible poly(ADP-ribose) polymerase).
    Title: Aryl hydrocarbon receptor activation by dioxin targets phosphoenolpyruvate carboxykinase (PEPCK) for ADP-ribosylation via 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-inducible poly(ADP-ribose) polymerase (TiPARP).
  3. Data show that hepatocellular carcinoma LMH cells transfected with a reporter construct bearing the vitellogenin promoter is a useful model for the study of hydrocarbon receptor (AHR)-estrogen receptor (ER) interaction in liver-derived cells.
    Title: Aryl hydrocarbon receptor activation leads to impairment of estrogen-driven chicken vitellogenin promoter activity in LMH cells.
Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables nuclear receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein dimerization activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transcription cis-regulatory region binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of aryl hydrocarbon receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
aryl hydrocarbon receptor

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_204118.3 → NP_989449.3  aryl hydrocarbon receptor

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000036
    UniProtKB/TrEMBL
    Q9I9E2, Q9PTI7
    Related
    ENSGALP00010006052.1, ENSGALT00010010358.1
    Conserved Domains (3) summary
    cd11436
    Location:25 → 85
    bHLH-PAS_AhR; basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in aryl hydrocarbon receptor (AhR) and similar proteins
    pfam00989
    Location:113 → 183
    PAS; PAS fold
    pfam14598
    Location:286 → 390
    PAS_11; PAS domain

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052533.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    28471720..28722202
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046917049.1 → XP_046773005.1  aryl hydrocarbon receptor isoform X1

    UniProtKB/TrEMBL
    A0A8V0XH72, Q9PTI7

  2. XM_046917058.1 → XP_046773014.1  aryl hydrocarbon receptor isoform X1

    UniProtKB/TrEMBL
    A0A8V0XH72, Q9PTI7

  3. XM_046917054.1 → XP_046773010.1  aryl hydrocarbon receptor isoform X1

    UniProtKB/TrEMBL
    A0A8V0XH72, Q9PTI7

  4. XM_046917064.1 → XP_046773020.1  aryl hydrocarbon receptor isoform X1

    UniProtKB/TrEMBL
    A0A8V0XH72, Q9PTI7

  5. XM_046917035.1 → XP_046772991.1  aryl hydrocarbon receptor isoform X1

    UniProtKB/TrEMBL
    A0A8V0XH72, Q9PTI7

  6. XM_046917033.1 → XP_046772989.1  aryl hydrocarbon receptor isoform X1

    UniProtKB/TrEMBL
    A0A8V0XH72, Q9PTI7

  7. XM_046917047.1 → XP_046773003.1  aryl hydrocarbon receptor isoform X1

    UniProtKB/TrEMBL
    A0A8V0XH72, Q9PTI7

  8. XM_046917034.1 → XP_046772990.1  aryl hydrocarbon receptor isoform X1

    UniProtKB/TrEMBL
    A0A8V0XH72, Q9PTI7

  9. XM_046917043.1 → XP_046772999.1  aryl hydrocarbon receptor isoform X1

    UniProtKB/TrEMBL
    A0A8V0XH72, Q9PTI7

  10. XM_046917072.1 → XP_046773028.1  aryl hydrocarbon receptor isoform X1

    UniProtKB/TrEMBL
    A0A8V0XH72, Q9PTI7

  11. XM_046917068.1 → XP_046773024.1  aryl hydrocarbon receptor isoform X1

    UniProtKB/TrEMBL
    A0A8V0XH72, Q9PTI7

  12. XM_046917079.1 → XP_046773035.1  aryl hydrocarbon receptor isoform X1

    UniProtKB/TrEMBL
    A0A8V0XH72, Q9PTI7

  13. XM_046917081.1 → XP_046773037.1  aryl hydrocarbon receptor isoform X1

    UniProtKB/TrEMBL
    A0A8V0XH72, Q9PTI7

  14. XM_046917076.1 → XP_046773032.1  aryl hydrocarbon receptor isoform X1

    UniProtKB/TrEMBL
    A0A8V0XH72, Q9PTI7

  15. XM_046917084.1 → XP_046773040.1  aryl hydrocarbon receptor isoform X1

    UniProtKB/TrEMBL
    A0A8V0XH72, Q9PTI7

  16. XM_040674084.2 → XP_040530018.1  aryl hydrocarbon receptor isoform X1

    UniProtKB/TrEMBL
    A0A8V0XH72, Q9PTI7
    Conserved Domains (3) summary
    smart00091
    Location:134 → 197
    PAS; PAS domain
    pfam08447
    Location:318 → 400
    PAS_3; PAS fold
    cd11436
    Location:44 → 104
    bHLH-PAS_AhR; basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in aryl hydrocarbon receptor (AhR) and similar proteins

  17. XM_040674083.2 → XP_040530017.1  aryl hydrocarbon receptor isoform X1

    UniProtKB/TrEMBL
    A0A8V0XH72, Q9PTI7
    Related
    ENSGALP00010006055.1, ENSGALT00010010364.1
    Conserved Domains (3) summary
    smart00091
    Location:134 → 197
    PAS; PAS domain
    pfam08447
    Location:318 → 400
    PAS_3; PAS fold
    cd11436
    Location:44 → 104
    bHLH-PAS_AhR; basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in aryl hydrocarbon receptor (AhR) and similar proteins

  18. XM_040674085.2 → XP_040530019.1  aryl hydrocarbon receptor isoform X1

    UniProtKB/TrEMBL
    A0A8V0XH72, Q9PTI7
    Conserved Domains (3) summary
    smart00091
    Location:134 → 197
    PAS; PAS domain
    pfam08447
    Location:318 → 400
    PAS_3; PAS fold
    cd11436
    Location:44 → 104
    bHLH-PAS_AhR; basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in aryl hydrocarbon receptor (AhR) and similar proteins

  19. XM_046917092.1 → XP_046773048.1  aryl hydrocarbon receptor isoform X2

    UniProtKB/TrEMBL
    A0A8V0XJU6
    Related
    ENSGALP00010006048.1, ENSGALT00010010351.1

  20. XM_040674087.2 → XP_040530021.1  aryl hydrocarbon receptor isoform X2

    UniProtKB/TrEMBL
    A0A8V0XJU6
    Conserved Domains (2) summary
    smart00091
    Location:42 → 105
    PAS; PAS domain
    pfam08447
    Location:226 → 308
    PAS_3; PAS fold

  21. XM_015281254.4 → XP_015136740.2  aryl hydrocarbon receptor isoform X3

    UniProtKB/TrEMBL
    A0A8V0XJV0
    Conserved Domains (1) summary
    pfam08447
    Location:144 → 226
    PAS_3; PAS fold

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052574.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    28504992..28755558
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046910155.1 → XP_046766111.1  aryl hydrocarbon receptor isoform X1

    UniProtKB/TrEMBL
    A0A8V0XH72, Q9PTI7

  2. XM_046910156.1 → XP_046766112.1  aryl hydrocarbon receptor isoform X1

    UniProtKB/TrEMBL
    A0A8V0XH72, Q9PTI7

  3. XM_046910160.1 → XP_046766116.1  aryl hydrocarbon receptor isoform X1

    UniProtKB/TrEMBL
    A0A8V0XH72, Q9PTI7

  4. XM_046910161.1 → XP_046766117.1  aryl hydrocarbon receptor isoform X1

    UniProtKB/TrEMBL
    A0A8V0XH72, Q9PTI7

  5. XM_046910158.1 → XP_046766114.1  aryl hydrocarbon receptor isoform X1

    UniProtKB/TrEMBL
    A0A8V0XH72, Q9PTI7

  6. XM_046910152.1 → XP_046766108.1  aryl hydrocarbon receptor isoform X1

    UniProtKB/TrEMBL
    A0A8V0XH72, Q9PTI7

  7. XM_046910149.1 → XP_046766105.1  aryl hydrocarbon receptor isoform X1

    UniProtKB/TrEMBL
    A0A8V0XH72, Q9PTI7

  8. XM_046910157.1 → XP_046766113.1  aryl hydrocarbon receptor isoform X1

    UniProtKB/TrEMBL
    A0A8V0XH72, Q9PTI7

  9. XM_046910151.1 → XP_046766107.1  aryl hydrocarbon receptor isoform X1

    UniProtKB/TrEMBL
    A0A8V0XH72, Q9PTI7

  10. XM_046910154.1 → XP_046766110.1  aryl hydrocarbon receptor isoform X1

    UniProtKB/TrEMBL
    A0A8V0XH72, Q9PTI7

  11. XM_046910150.1 → XP_046766106.1  aryl hydrocarbon receptor isoform X1

    UniProtKB/TrEMBL
    A0A8V0XH72, Q9PTI7

  12. XM_046910162.1 → XP_046766118.1  aryl hydrocarbon receptor isoform X1

    UniProtKB/TrEMBL
    A0A8V0XH72, Q9PTI7

  13. XM_046910159.1 → XP_046766115.1  aryl hydrocarbon receptor isoform X1

    UniProtKB/TrEMBL
    A0A8V0XH72, Q9PTI7

  14. XM_046910163.1 → XP_046766119.1  aryl hydrocarbon receptor isoform X1

    UniProtKB/TrEMBL
    A0A8V0XH72, Q9PTI7

  15. XM_046910165.1 → XP_046766121.1  aryl hydrocarbon receptor isoform X1

    UniProtKB/TrEMBL
    A0A8V0XH72, Q9PTI7

  16. XM_046910164.1 → XP_046766120.1  aryl hydrocarbon receptor isoform X1

    UniProtKB/TrEMBL
    A0A8V0XH72, Q9PTI7

  17. XM_046910167.1 → XP_046766123.1  aryl hydrocarbon receptor isoform X1

    UniProtKB/TrEMBL
    A0A8V0XH72, Q9PTI7

  18. XM_046910153.1 → XP_046766109.1  aryl hydrocarbon receptor isoform X1

    UniProtKB/TrEMBL
    A0A8V0XH72, Q9PTI7

  19. XM_046910168.1 → XP_046766124.1  aryl hydrocarbon receptor isoform X1

    UniProtKB/TrEMBL
    A0A8V0XH72, Q9PTI7

  20. XM_046910166.1 → XP_046766122.1  aryl hydrocarbon receptor isoform X1

    UniProtKB/TrEMBL
    A0A8V0XH72, Q9PTI7

  21. XM_046910169.1 → XP_046766125.1  aryl hydrocarbon receptor isoform X1

    UniProtKB/TrEMBL
    A0A8V0XH72, Q9PTI7

  22. XM_046910171.1 → XP_046766127.1  aryl hydrocarbon receptor isoform X2

    UniProtKB/TrEMBL
    A0A8V0XJU6

  23. XM_046910170.1 → XP_046766126.1  aryl hydrocarbon receptor isoform X2

    UniProtKB/TrEMBL
    A0A8V0XJU6

  24. XM_046910172.1 → XP_046766128.1  aryl hydrocarbon receptor isoform X3

    UniProtKB/TrEMBL
    A0A8V0XJV0
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.