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H5R temporal expression: early/late [ Vaccinia virus ]

Gene ID: 3707559, updated on 18-Aug-2023

Summary

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Gene symbol
H5R
Gene description
temporal expression: early/late
Locus tag
VACWR103
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Vaccinia virus (strain: WR (Western Reserve))
Lineage
Viruses; dsDNA viruses, no RNA stage; Poxviridae; Chordopoxvirinae; Orthopoxvirus
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Genomic context

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Sequence:
NC_006998.1 (91871..92482)

NC_006998.1Genomic Context describing neighboring genes Neighboring gene temporal expression: late Neighboring gene temporal expression: late Neighboring gene DNA topoisomerase type I Neighboring gene temporal expression: late

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_006998.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Vaccinia H5 is a multifunctional protein involved in viral DNA replication, postreplicative gene transcription, and virion morphogenesis. D'Costa SM, et al. Virology, 2010 May 25. PMID 20206959, Free PMC Article
  2. Genomic analysis of the vaccinia virus strain variants found in Dryvax vaccine. Qin L, et al. J Virol, 2011 Dec. PMID 21976639, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. H5R viral protein plays roles in vaccinia virus DNA replication, transcription and morphogenesis in vivo.
    Title: Vaccinia H5 is a multifunctional protein involved in viral DNA replication, postreplicative gene transcription, and virion morphogenesis.
Submit: New GeneRIF Correction

General gene information

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Homology

General protein information

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Preferred Names
late transcription factor VLTF-4
YP_232985.1
  • late transcription factor VLTF-4; initiates transcription from late gene promoters; inhibition of DNA replication causes VLTF-4 to be diffusely distributed in the cytoplasm but is discretely localized during a productive infection; The poxviridae are enveloped unsegmented dsDNA viruses; unlike many dsDNA viruses that replicate in the host nucleus poxviruses encode their own replication machinery and therefore replicate in the cytoplasm; viral genes are expressed in a bi-phasic manner with early genes encoding non-structural proteins involved in genome replication and late genes encoding the viral structural proteins

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_006998.1 Reference assembly

    Range
    91871..92482
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. YP_232985.1 morphogenesis-related, substrate of B1R kinase [Vaccinia virus]

    See identical proteins and their annotated locations for YP_232985.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P07242, P20538, Q76ZS8
    UniProtKB/TrEMBL
    A0A0A1CTA0, A0A2I2MC42, A9J1S6, M9WGD8, Q1PIU6, Q6RZJ9, Q76RC5, Q77TK2, V5R1G2
    Conserved Domains (1) summary
    PHA03089
    Location:1 → 189
    PHA03089; late transcription factor VLTF-4; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
2106269A.1
AAO89382.1

Gene LinkOut

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