U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Syngr Synaptogyrin [ Drosophila melanogaster (fruit fly) ]

Gene ID: 36533, updated on 18-Sep-2024

Summary

Go to the top of the page Help
Official Symbol
Syngrprovided by FlyBase
Official Full Name
Synaptogyrinprovided by FlyBase
Primary source
FLYBASE:FBgn0033876
Locus tag
Dmel_CG10808
See related
AllianceGenome:FB:FBgn0033876
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG10808; Dmel\CG10808; gyr; Gyr; sng-1; synaptogyrin
Summary
Involved in synaptic vesicle transport. Predicted to be active in neuromuscular junction and synaptic vesicle membrane. Is expressed in adult head; embryonic/larval central nervous system; and embryonic/larval neuromuscular junction. Orthologous to several human genes including SYNGR1 (synaptogyrin 1) and SYNGR3 (synaptogyrin 3). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Syngr in Genome Data Viewer
Location:
50C6-50C6; 2-68 cM
Exon count:
5
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (13841761..13846255, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (9729266..9733760, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Cathepsin L2 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene mir-9379 stem loop

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Two Pathways for the Activity-Dependent Growth and Differentiation of Synaptic Boutons in Drosophila. Vasin A, et al. eNeuro, 2019 Jul/Aug. PMID 31387877, Free PMC Article
  2. Abnormal synaptic vesicle biogenesis in Drosophila synaptogyrin mutants. Stevens RJ, et al. J Neurosci, 2012 Dec 12. PMID 23238721, Free PMC Article
  3. Differential regulation of evoked and spontaneous neurotransmitter release by C-terminal modifications of complexin. Buhl LK, et al. Mol Cell Neurosci, 2013 Jan. PMID 23159779, Free PMC Article
  4. Discovery of insect and human dengue virus host factors. Sessions OM, et al. Nature, 2009 Apr 23. PMID 19396146, Free PMC Article
  5. Ligand binding-dependent functions of the lipocalin NLaz: an in vivo study in Drosophila. Ruiz M, et al. FASEB J, 2014 Apr. PMID 24361577

See all (42) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in synaptic vesicle exocytosis ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
involved_in synaptic vesicle transport IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in synaptic vesicle transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in neuromuscular junction IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in synaptic vesicle membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
synaptogyrin
Names
CG10808-PA
Syngr-PA

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    13841761..13846255 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_137064.3 → NP_610908.1  synaptogyrin [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_610908.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q7JYV2
    Related
    FBpp0086771
    Conserved Domains (1) summary
    pfam01284
    Location:34 → 169
    MARVEL; Membrane-associating domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q7JYV2.1 Q7JYV2

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Molecular Biology Databases
Research Materials
Tools
Miscellaneous