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Trappc3 trafficking protein particle complex subunit 3 [ Rattus norvegicus (Norway rat) ]

Gene ID: 362599, updated on 10-Jul-2024

Summary

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Official Symbol
Trappc3provided by RGD
Official Full Name
trafficking protein particle complex subunit 3provided by RGD
Primary source
RGD:1309135
See related
EnsemblRapid:ENSRNOG00000010550 AllianceGenome:RGD:1309135
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport and intra-Golgi vesicle-mediated transport. Predicted to be located in Golgi membrane. Predicted to be part of TRAPP complex. Predicted to be active in cis-Golgi network membrane and cytosol. Orthologous to human TRAPPC3 (trafficking protein particle complex subunit 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Brain (RPKM 245.6), Kidney (RPKM 234.1) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Trappc3 in Genome Data Viewer
Location:
5q36
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (143843612..143857347)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (138559238..138572825)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (144281720..144295306)

Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120103176 Neighboring gene MAP7 domain containing 1 Neighboring gene uncharacterized LOC134486990 Neighboring gene collagen type VIII alpha 2 chain Neighboring gene ADP-ribosylserine hydrolase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Mammalian Bet3 functions as a cytosolic factor participating in transport from the ER to the Golgi apparatus. Loh E, et al. J Cell Sci, 2005 Mar 15. PMID 15728249
  2. mBET3 is required for the organization of the TRAPP complexes. Menon S, et al. Biochem Biophys Res Commun, 2006 Nov 24. PMID 17027922
  3. C4orf41 and TTC-15 are mammalian TRAPP components with a role at an early stage in ER-to-Golgi trafficking. Scrivens PJ, et al. Mol Biol Cell, 2011 Jun 15. PMID 21525244, Free PMC Article
  4. Identification and characterization of the BRI2 interactome in the brain. Martins F, et al. Sci Rep, 2018 Feb 23. PMID 29476059, Free PMC Article
  5. Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis. Na CH, et al. J Proteome Res, 2012 Sep 7. PMID 22871113, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Bet3 functions as a cytosolic factor participating in transport from the ER to the Golgi apparatus
    Title: Mammalian Bet3 functions as a cytosolic factor participating in transport from the ER to the Golgi apparatus.
Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • MGC105948

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in Golgi vesicle transport IEA
Inferred from Electronic Annotation
more info
  
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within endoplasmic reticulum to Golgi vesicle-mediated transport ISO
Inferred from Sequence Orthology
more info
  
involved_in intra-Golgi vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
  
located_in Golgi apparatus ISO
Inferred from Sequence Orthology
more info
  
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
  
located_in Golgi membrane ISO
Inferred from Sequence Orthology
more info
  
part_of TRAPP complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of TRAPP complex IEA
Inferred from Electronic Annotation
more info
  
part_of TRAPP complex ISO
Inferred from Sequence Orthology
more info
  
is_active_in cis-Golgi network membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytosol IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
trafficking protein particle complex subunit 3
Names
BET3 homolog
trafficking protein particle complex 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001008376.1 → NP_001008377.1  trafficking protein particle complex subunit 3

    See identical proteins and their annotated locations for NP_001008377.1

    Status: PROVISIONAL

    Source sequence(s)
    BC086377
    UniProtKB/Swiss-Prot
    Q5U1Z2
    UniProtKB/TrEMBL
    A0A8L2Q6T4, A6ISA1
    Related
    ENSRNOP00000014383.5, ENSRNOT00000014383.8
    Conserved Domains (1) summary
    cd14942
    Location:15 → 169
    TRAPPC3_bet3; Bet3-TRAPPC3 subunit of the TRAPP complex

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086023.1 Reference GRCr8

    Range
    143843612..143857347
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063288019.1 → XP_063144089.1  trafficking protein particle complex subunit 3 isoform X1

  2. XM_063288021.1 → XP_063144091.1  trafficking protein particle complex subunit 3 isoform X2

  3. XM_039110349.1 → XP_038966277.1  trafficking protein particle complex subunit 3 isoform X3

    Conserved Domains (1) summary
    cd14942
    Location:1 → 85
    TRAPPC3_bet3; Bet3-TRAPPC3 subunit of the TRAPP complex

  4. XM_063288020.1 → XP_063144090.1  trafficking protein particle complex subunit 3 isoform X1

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5U1Z2.1 GenPept UniProtKB/Swiss-Prot:Q5U1Z2

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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