Cabp7 calcium binding protein 7 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Cabp7provided by RGD
Official Full Name: calcium binding protein 7provided by RGD
Primary source: RGD:1359269
See related: EnsemblRapid:ENSRNOG00000057703 AllianceGenome:RGD:1359269
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: rCaBP7
Summary: Predicted to enable calcium ion binding activity. Predicted to be located in perinuclear region of cytoplasm and plasma membrane. Predicted to be active in trans-Golgi network membrane. Orthologous to human CABP7 (calcium binding protein 7). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in Brain (RPKM 82.9), Adrenal (RPKM 15.9) and 7 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 14q21

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	14	NC_086032.1 (83822322..83832667, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	14	NC_051349.1 (79598822..79609172, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	14	NC_005113.4 (84968125..84978242, complement)

Chromosome 14 - NC_086032.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

calneuron-1 and calneuron-2 physically associate with PI-4Kbeta, inhibit the enzyme profoundly at resting and low calcium levels, and negatively interfere with Golgi-to-plasma membrane trafficking.
Title: Calneurons provide a calcium threshold for trans-Golgi network to plasma membrane trafficking.
The calcium sensor protein caldendrin is abundantly expressed in neurons and is thought to play an important role in different aspects of synapto-dendritic Ca2+ signaling.
Title: Neuronal Ca2+ signaling via caldendrin and calneurons.

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General gene information

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Markers

NoName (e-PCR)
- UniSTS:493089

RH141041 (e-PCR)
- UniSTS:223041

N28202 (e-PCR)
- UniSTS:125505

NoName (e-PCR)
- UniSTS:490581

RH144089 (e-PCR)
- UniSTS:233335

RH143960 (e-PCR)
- UniSTS:233206

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables calcium ion binding	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in perinuclear region of cytoplasm	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info
is_active_in trans-Golgi network membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in trans-Golgi network membrane	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: calcium-binding protein 7

Names: calneuron-2; calneuron-II

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.