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Rpl23a ribosomal protein L23A [ Rattus norvegicus (Norway rat) ]

Gene ID: 360572, updated on 2-Nov-2024

Summary

Official Symbol
Rpl23aprovided by RGD
Official Full Name
ribosomal protein L23Aprovided by RGD
Primary source
RGD:1304897
See related
EnsemblRapid:ENSRNOG00000023344 AllianceGenome:RGD:1304897
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Enables large ribosomal subunit rRNA binding activity. Predicted to be involved in translation. Part of cytosolic large ribosomal subunit. Orthologous to human RPL23A (ribosomal protein L23a). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Spleen (RPKM 3823.4), Thymus (RPKM 3439.0) and 9 other tissues See more
Orthologs
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Genomic context

See Rpl23a in Genome Data Viewer
Location:
10q25
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (63574732..63577511, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (63076660..63079346, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (65441295..65443981, complement)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene NIMA-related kinase 8 Neighboring gene TLC domain containing 1 Neighboring gene small nucleolar RNA, C/D box 42A Neighboring gene small nucleolar RNA, C/D box 4A Neighboring gene small nucleolar RNA, C/D box 42B Neighboring gene RAB34, member RAS oncogene family Neighboring gene protein interacting with cyclin A1

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables TORC2 complex binding ISO
Inferred from Sequence Orthology
more info
 
enables TORC2 complex binding ISS
Inferred from Sequence or Structural Similarity
more info
 
enables large ribosomal subunit rRNA binding IDA
Inferred from Direct Assay
more info
PubMed 
enables rRNA binding IEA
Inferred from Electronic Annotation
more info
 
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
 
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
 
enables structural constituent of ribosome ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
involved_in translation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
part_of cytosolic large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of cytosolic large ribosomal subunit IDA
Inferred from Direct Assay
more info
PubMed 
part_of cytosolic large ribosomal subunit ISO
Inferred from Sequence Orthology
more info
 
located_in cytosolic ribosome ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
 
part_of ribosomal subunit IEA
Inferred from Electronic Annotation
more info
 
is_active_in synapse ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
large ribosomal subunit protein uL23
Names
60S ribosomal protein L23a

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001108283.1NP_001101753.1  large ribosomal subunit protein uL23

    See identical proteins and their annotated locations for NP_001101753.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473948
    UniProtKB/Swiss-Prot
    P62752
    UniProtKB/TrEMBL
    B5DES1, D3ZTX9
    Related
    ENSRNOP00000036391.5, ENSRNOT00000035657.5
    Conserved Domains (1) summary
    PTZ00191
    Location:36156
    PTZ00191; 60S ribosomal protein L23a; Provisional

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    63574732..63577511 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063269378.1XP_063125448.1  large ribosomal subunit protein uL23 isoform X1

    UniProtKB/TrEMBL
    A0A8L2QIC1