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CG1513 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 36028, updated on 2-Nov-2024

Summary

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Official Symbol
CG1513provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0033463
Locus tag
Dmel_CG1513
See related
AllianceGenome:FB:FBgn0033463
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG1513
Summary
Predicted to enable sterol binding activity. Predicted to be active in Golgi apparatus; cytosol; and membrane. Is expressed in adult head; wing hinge primordium; and wing pouch. Orthologous to human OSBPL9 (oxysterol binding protein like 9). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

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See CG1513 in Genome Data Viewer
Location:
46C2-46C2; 2-61 cM
Exon count:
16
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (9882572..9891689, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (5770077..5779194, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene pendolino Neighboring gene Linking immunity and metabolism Neighboring gene uncharacterized protein Neighboring gene Secretory 24AB Neighboring gene antisense RNA:CR45467 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene telomere ends associated Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The amyotrophic lateral sclerosis 8 protein, VAP, is required for ER protein quality control. Moustaqim-Barrette A, et al. Hum Mol Genet, 2014 Apr 15. PMID 24271015, Free PMC Article
  2. OSBP- and FAN-mediated sterol requirement for spermatogenesis in Drosophila. Ma Z, et al. Development, 2010 Nov. PMID 20943709
  3. PI(4)P Promotes Phosphorylation and Conformational Change of Smoothened through Interaction with Its C-terminal Tail. Jiang K, et al. PLoS Biol, 2016 Feb. PMID 26863604, Free PMC Article
  4. Protein correlation profiles identify lipid droplet proteins with high confidence. Krahmer N, et al. Mol Cell Proteomics, 2013 May. PMID 23319140, Free PMC Article
  5. A genome engineering resource to uncover principles of cellular organization and tissue architecture by lipid signaling. Trivedi D, et al. Elife, 2020 Dec 15. PMID 33320085, Free PMC Article

See all (35) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables lipid binding IEA
Inferred from Electronic Annotation
more info
  
enables sterol binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG1513-PA
CG1513-PB
CG1513-PC
oxysterol binding protein

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    9882572..9891689 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_136690.5 → NP_610534.3  uncharacterized protein Dmel_CG1513, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_610534.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    A1Z814, D3DMG7
    Conserved Domains (3) summary
    cd13290
    Location:24 → 125
    PH_ORP9; Human Oxysterol binding protein related protein 9 Pleckstrin homology (PH) domain
    pfam00169
    Location:25 → 118
    PH; PH domain
    pfam01237
    Location:421 → 767
    Oxysterol_BP; Oxysterol-binding protein

  2. NM_001273909.1 → NP_001260838.1  uncharacterized protein Dmel_CG1513, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001260838.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0B4KEI3
    Conserved Domains (1) summary
    pfam01237
    Location:106 → 452
    Oxysterol_BP; Oxysterol-binding protein

  3. NM_001169633.2 → NP_001163104.1  uncharacterized protein Dmel_CG1513, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001163104.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    E1JH23
    Conserved Domains (1) summary
    pfam01237
    Location:106 → 399
    Oxysterol_BP; Oxysterol-binding protein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A0A0B4KEI3 A0A0B4KEI3
A1Z814 A1Z814
E1JH23 E1JH23

Gene LinkOut

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