U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Mal-B1 Maltase B1 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 34597, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
Mal-B1provided by FlyBase
Official Full Name
Maltase B1provided by FlyBase
Primary source
FLYBASE:FBgn0032381
Locus tag
Dmel_CG14934
See related
AllianceGenome:FB:FBgn0032381
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG14934; Dmel\CG14934; Drome_B1; mal_B1
Summary
Enables alpha-1,4-glucosidase activity. Predicted to be involved in carbohydrate metabolic process. Is expressed in adult fat body and adult head. Human ortholog(s) of this gene implicated in cystinuria. Orthologous to human SLC3A1 (solute carrier family 3 member 1). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Mal-B1 in Genome Data Viewer
Location:
33A3-33A4; 2-45 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (11847226..11849169)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (11847226..11849169)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Phosphodiesterase 1c Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Maltase B2 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. AGI, a previously unreported D. melanogaster alpha-glucosidase: partial purification, characterization, and cytogenetic mapping. Parker GF, et al. Biochem Genet, 1996 Apr. PMID 8734412
  2. Comparative Transcriptomic Analysis Revealing the Potential Mechanisms of Erythritol-Caused Mortality and Oviposition Inhibition in Drosophila melanogaster. Li L, et al. Int J Mol Sci, 2024 Mar 27. PMID 38612549, Free PMC Article
  3. Neural clocks and Neuropeptide F/Y regulate circadian gene expression in a peripheral metabolic tissue. Erion R, et al. Elife, 2016 Apr 14. PMID 27077948, Free PMC Article
  4. Association between duplicated maltase genes and the transcriptional regulation for the carbohydrate changes in Drosophila melanogaster. Inomata N, et al. Gene, 2019 Feb 20. PMID 30399425
  5. Assessment of genome-wide protein function classification for Drosophila melanogaster. Mi H, et al. Genome Res, 2003 Sep. PMID 12952880, Free PMC Article

See all (47) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables alpha-1,4-glucosidase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables alpha-1,4-glucosidase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
maltase B1
Names
CG14934-PA
Mal-B1-PA
NP_609522.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    11847226..11849169
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_135678.2 → NP_609522.1  maltase B1 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_609522.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    B5RJ23, Q9VKE6
    Related
    FBpp0079859
    Conserved Domains (2) summary
    cd11328
    Location:30 → 500
    AmyAc_maltase; Alpha amylase catalytic domain found in maltase (also known as alpha glucosidase) and related proteins
    TIGR02403
    Location:33 → 538
    trehalose_treC; alpha,alpha-phosphotrehalase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VKE6 Q9VKE6

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools
Miscellaneous