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IDDM7 insulin dependent diabetes mellitus 7 [ Homo sapiens (human) ]

Gene ID: 3406, updated on 31-Aug-2024

Summary

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Official Symbol
IDDM7provided by HGNC
Official Full Name
insulin dependent diabetes mellitus 7provided by HGNC
Primary source
MIM:600321
Gene type
unknown
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo

Genomic context

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Location:
2q31

Bibliography

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Related articles in PubMed

  1. The HOXD8 locus (2q31) is linked to type I diabetes. Interaction with chromosome 6 and 11 disease susceptibility genes. Owerbach D, et al. Diabetes, 1995 Jan. PMID 7813807
  2. Through regulation of TCR expression levels, an Idd7 region gene(s) interactively contributes to the impaired thymic deletion of autoreactive diabetogenic CD8+ T cells in nonobese diabetic mice. Serreze DV, et al. J Immunol, 2008 Mar 1. PMID 18292549
  3. Confirmation of three susceptibility genes to insulin-dependent diabetes mellitus: IDDM4, IDDM5 and IDDM8. Luo DF, et al. Hum Mol Genet, 1996 May. PMID 8733139

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. IDDM7 susceptibility genes, both within and outside the histocompatibility comlex, may interact to elicit autoreactive T cell responses mediating development of type 1 diabetes in both NOD mice and human patients.
    Title: Through regulation of TCR expression levels, an Idd7 region gene(s) interactively contributes to the impaired thymic deletion of autoreactive diabetogenic CD8+ T cells in nonobese diabetic mice.
Submit: New GeneRIF Correction

Phenotypes

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Associated conditions

Description Tests
insulin dependent diabetes mellitus 7
OMIM: 600321GeneReviews: Not available

General gene information

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Markers

Property

  • phenotype only

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