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CG5958 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 34022, updated on 2-Nov-2024

Summary

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Official Symbol
CG5958provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0031913
Locus tag
Dmel_CG5958
See related
AllianceGenome:FB:FBgn0031913
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG5958
Summary
Predicted to enable phosphatidylinositol bisphosphate binding activity and retinal binding activity. Predicted to be involved in response to light stimulus. Located in cytoplasm. Is expressed in several structures, including adult head; adult heart; amnioserosa; embryonic/larval hemocyte; and visceral mesoderm derivative. Human ortholog(s) of this gene implicated in Bothnia retinal dystrophy; Newfoundland cone-rod dystrophy; fundus albipunctatus; night blindness; and retinitis pigmentosa. Orthologous to several human genes including TTPAL (alpha tocopherol transfer protein like). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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See CG5958 in Genome Data Viewer
Location:
27F4-27F4; 2-26 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (7430530..7433516, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (7430530..7433516, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene mir-305 stem loop Neighboring gene midline uncoordinated Neighboring gene uncharacterized protein Neighboring gene scavenger receptor acting in neural tissue and majority of rhodopsin is absent Neighboring gene Gustatory receptor 28a

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Dissection of the pathway required for generation of vitamin A and for Drosophila phototransduction. Wang T, et al. J Cell Biol, 2007 Apr 23. PMID 17452532, Free PMC Article
  2. Genome-wide transcriptional orchestration of circadian rhythms in Drosophila. Ueda HR, et al. J Biol Chem, 2002 Apr 19. PMID 11854264
  3. During Drosophila disc regeneration, JAK/STAT coordinates cell proliferation with Dilp8-mediated developmental delay. Katsuyama T, et al. Proc Natl Acad Sci U S A, 2015 May 5. PMID 25902518, Free PMC Article
  4. Characterization of the Drosophila lipid droplet subproteome. Beller M, et al. Mol Cell Proteomics, 2006 Jun. PMID 16543254
  5. Gene expression during the life cycle of Drosophila melanogaster. Arbeitman MN, et al. Science, 2002 Sep 27. PMID 12351791

See all (37) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables phosphatidylinositol bisphosphate binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables retinal binding ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in response to light stimulus ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 

General protein information

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Preferred Names
uncharacterized protein
Names
CG5958-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    7430530..7433516 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_135275.3 → NP_609119.2  uncharacterized protein Dmel_CG5958 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_609119.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8SYZ8, Q9VM12
    Related
    FBpp0079090
    Conserved Domains (2) summary
    smart01100
    Location:38 → 82
    CRAL_TRIO_N; CRAL/TRIO, N-terminal domain
    pfam00650
    Location:111 → 261
    CRAL_TRIO; CRAL/TRIO domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8SYZ8 Q8SYZ8
Q9VM12 Q9VM12

Gene LinkOut

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