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swr1 Swr1 complex histone chaperone module subunit, SNF2 family ATP-dependent chromatin remodeller Swr1 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 3361561, updated on 22-Jun-2024

Summary

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Gene symbol
swr1
Gene description
Swr1 complex histone chaperone module subunit, SNF2 family ATP-dependent chromatin remodeller Swr1
Locus tag
SPOM_SPAC11E3.01C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
mod22; SPAC2H10.03c
Old locus tag
SPAC11E3.01c
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Genomic context

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See swr1 in Genome Data Viewer
Location:
chromosome: I
Exon count:
1
Sequence:
Chromosome: I; NC_003424.3 (5277395..5281407, complement)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene transcription factor Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene 26S proteasome regulatory particle assembly protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Munc family exocytic/endocytic regulator Ync13

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Podbat: a novel genomic tool reveals Swr1-independent H2A.Z incorporation at gene coding sequences through epigenetic meta-analysis. Sadeghi L, et al. PLoS Comput Biol, 2011 Aug. PMID 21901086, Free PMC Article
  2. Improved tools for efficient mapping of fission yeast genes: identification of microtubule nucleation modifier mod22-1 as an allele of chromatin- remodelling factor gene swr1. Anders A, et al. Yeast, 2008 Dec. PMID 19160458, Free PMC Article
  3. Activity of a C-terminal plant homeodomain (PHD) of Msc1 is essential for function. Qiu X, et al. J Biol Chem, 2010 Nov 19. PMID 20858896, Free PMC Article
  4. The Schizosaccharomyces pombe JmjC-protein, Msc1, prevents H2A.Z localization in centromeric and subtelomeric chromatin domains. Buchanan L, et al. PLoS Genet, 2009 Nov. PMID 19911051, Free PMC Article
  5. Histone variant H2A.Z regulates centromere silencing and chromosome segregation in fission yeast. Hou H, et al. J Biol Chem, 2010 Jan 15. PMID 19910462, Free PMC Article

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Mod22-1, a modifier of microtubule nucleation phenotypes, encodes a truncation allele of Swr1, a chromatin-remodelling factor involved in nucleosomal deposition of H2A.Z histone variant Pht1.
    Title: Improved tools for efficient mapping of fission yeast genes: identification of microtubule nucleation modifier mod22-1 as an allele of chromatin- remodelling factor gene swr1.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables ATP binding ISM
Inferred from Sequence Model
more info
  
enables ATP hydrolysis activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ATP-dependent H2AZ histone chaperone activity EXP
Inferred from Experiment
more info
 PubMed 
enables DNA binding IC
Inferred by Curator
more info
  
enables histone binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables peptide N-acetyltransferase activity EXP
Inferred from Experiment
more info
 PubMed 
Process Evidence Code Pubs
involved_in chromatin remodeling IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in transcription initiation-coupled chromatin remodeling IC
Inferred by Curator
more info
  
Component Evidence Code Pubs
part_of Swr1 complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of Swr1 complex IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nucleus HDA PubMed 

General protein information

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Preferred Names
Swr1 complex histone chaperone module subunit, SNF2 family ATP-dependent chromatin remodeller Swr1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    5277395..5281407 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001356200.2 → NP_001342781.1  Swr1 complex histone chaperone module subunit, SNF2 family ATP-dependent chromatin remodeller Swr1 [Schizosaccharomyces pombe]

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O13682, Q9URL5
    Conserved Domains (3) summary
    pfam00176
    Location:450 → 745
    SNF2_N; SNF2 family N-terminal domain
    pfam07529
    Location:116 → 177
    HSA; HSA
    cl26465
    Location:991 → 1145
    SNF2_N; SNF2 family N-terminal domain
Nucleotide Protein
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