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NLaz Neural Lazarillo [ Drosophila melanogaster (fruit fly) ]

Gene ID: 33324, updated on 18-Sep-2024

Summary

Official Symbol
NLazprovided by FlyBase
Official Full Name
Neural Lazarilloprovided by FlyBase
Primary source
FLYBASE:FBgn0053126
Locus tag
Dmel_CG33126
See related
AllianceGenome:FB:FBgn0053126
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BcDNA:RE67583; CG16933; CG33126; CT33980; Dmel\CG33126; DNLaz; nlaz; Nlaz
Summary
Predicted to enable pigment binding activity. Involved in several processes, including carbohydrate homeostasis; determination of adult lifespan; and triglyceride homeostasis. Located in extracellular space. Is expressed in several structures, including aCC neuron; central nervous system; extended germ band embryo; gut; and ventral midline of embryo. Human ortholog(s) of this gene implicated in obesity and type 2 diabetes mellitus. Orthologous to human APOD (apolipoprotein D). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See NLaz in Genome Data Viewer
Location:
22A1-22A1; 2-3 cM
Exon count:
6
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (1359837..1361821, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (1359837..1361821, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44898 Neighboring gene antisense RNA:CR44897 Neighboring gene roundabout 2

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
neural lazarillo
Names
CG33126-PA
CG33126-PB
CG33126-PC
NLaz-PA
NLaz-PB
NLaz-PC

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    1359837..1361821 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001298631.1NP_001285560.1  neural lazarillo, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001285560.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8SXR1, Q9NAZ4, Q9VQ05
    Conserved Domains (1) summary
    cl21528
    Location:36164
    Lipocalin; Lipocalin / cytosolic fatty-acid binding protein family
  2. NM_175946.2NP_787960.1  neural lazarillo, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_787960.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8SXR1, Q9NAZ4, Q9VQ05
    Related
    FBpp0077607
    Conserved Domains (1) summary
    cl21528
    Location:36164
    Lipocalin; Lipocalin / cytosolic fatty-acid binding protein family
  3. NM_001272938.2NP_001259867.1  neural lazarillo, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001259867.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9PBN2, Q9NAZ4
    Conserved Domains (1) summary
    cl21528
    Location:36164
    Lipocalin; Lipocalin / cytosolic fatty-acid binding protein family