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qrsl1 glutaminyl-tRNA amidotransferase subunit QRSL1 [ Danio rerio (zebrafish) ]

Gene ID: 327329, updated on 2-Nov-2024

Summary

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Official Symbol
qrsl1provided by ZNC
Official Full Name
glutaminyl-tRNA amidotransferase subunit QRSL1provided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-5540
See related
Ensembl:ENSDARG00000032704 AllianceGenome:ZFIN:ZDB-GENE-030131-5540
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
wu:fi03b10
Summary
Predicted to enable glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity. Predicted to be involved in glutaminyl-tRNAGln biosynthesis via transamidation and mitochondrial translation. Predicted to act upstream of or within translation. Predicted to be part of glutamyl-tRNA(Gln) amidotransferase complex. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 40. Orthologous to human QRSL1 (glutaminyl-tRNA amidotransferase subunit QRSL1). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See qrsl1 in Genome Data Viewer
Location:
chromosome: 17
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 17 NC_007128.7 (25563977..25576204)
105 previous assembly GRCz10 (GCF_000002035.5) 17 NC_007128.6 (25545586..25557813)

Chromosome 17 - NC_007128.7Genomic Context describing neighboring genes Neighboring gene chloride intracellular channel 4 Neighboring gene crystallin beta-gamma domain containing 1a Neighboring gene reticulon 4 interacting protein 1 Neighboring gene si:ch211-214p16.1 Neighboring gene si:ch211-214p16.2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Nxhl Controls Angiogenesis by Targeting VE-PTP Through Interaction With Nucleolin. Luo H, et al. Front Cell Dev Biol, 2021. PMID 34733844, Free PMC Article
  2. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article
  3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • FLJ10989

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables catalytic activity IEA
Inferred from Electronic Annotation
more info
  
enables glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity IEA
Inferred from Electronic Annotation
more info
  
enables ligase activity IEA
Inferred from Electronic Annotation
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in glutaminyl-tRNAGln biosynthesis via transamidation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mitochondrial translation IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of glutamyl-tRNA(Gln) amidotransferase complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of glutamyl-tRNA(Gln) amidotransferase complex IEA
Inferred from Electronic Annotation
more info
  
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial
Names
QRSL1, glutaminyl-tRNA amidotransferase subunit A
glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1
NP_001112370.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001118898.1 → NP_001112370.1  glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial

    See identical proteins and their annotated locations for NP_001112370.1

    Status: PROVISIONAL

    Source sequence(s)
    FP015823
    UniProtKB/Swiss-Prot
    F1QAJ4, Q803A5
    Related
    ENSDARP00000045614.5, ENSDART00000045615.6
    Conserved Domains (2) summary
    PRK00012
    Location:26 → 502
    gatA; aspartyl/glutamyl-tRNA amidotransferase subunit A; Reviewed
    PRK07488
    Location:17 → 505
    PRK07488; indole acetimide hydrolase; Validated

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007128.7 Reference GRCz11 Primary Assembly

    Range
    25563977..25576204
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
F1QAJ4.1 GenPept UniProtKB/Swiss-Prot:F1QAJ4

Gene LinkOut

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