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mphosph10 M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) [ Danio rerio (zebrafish) ]

Gene ID: 323426, updated on 2-Nov-2024

Summary

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Official Symbol
mphosph10provided by ZNC
Official Full Name
M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)provided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-2146
See related
Ensembl:ENSDARG00000012495 AllianceGenome:ZFIN:ZDB-GENE-030131-2146
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fb98b07; wu:fb98b07
Summary
Acts upstream of or within digestive system development. Part of Mpp10 complex. Is expressed in several structures, including brain; digestive system; liver; and unfertilized egg. Orthologous to human MPHOSPH10 (M-phase phosphoprotein 10). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See mphosph10 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (30772991..30779569, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (30501841..30508419, complement)

Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene myosin IEa Neighboring gene myotubularin related protein 10 Neighboring gene methylmalonyl CoA epimerase Neighboring gene amyloid beta (A4) precursor protein-binding, family A, member 2b

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. An equation to estimate the difference between theoretically predicted and SDS PAGE-displayed molecular weights for an acidic peptide. Guan Y, et al. Sci Rep, 2015 Aug 27. PMID 26311515, Free PMC Article
  2. Sas10 controls ribosome biogenesis by stabilizing Mpp10 and delivering the Mpp10-Imp3-Imp4 complex to nucleolus. Zhao S, et al. Nucleic Acids Res, 2019 Apr 8. PMID 30773582, Free PMC Article
  3. Analysis of gene network bifurcation during optic cup morphogenesis in zebrafish. Buono L, et al. Nat Commun, 2021 Jun 23. PMID 34162866, Free PMC Article
  4. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article
  5. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within digestive system development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within rRNA processing IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within ribosome biogenesis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of Mpp10 complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of Mpp10 complex IEA
Inferred from Electronic Annotation
more info
  
part_of Mpp10 complex IPI
Inferred from Physical Interaction
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  
part_of small-subunit processome IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of sno(s)RNA-containing ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
U3 small nucleolar ribonucleoprotein protein MPP10

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001305543.1 → NP_001292472.1  U3 small nucleolar ribonucleoprotein protein MPP10

    Status: VALIDATED

    Source sequence(s)
    BX663518, CT645171, EB912193
    UniProtKB/TrEMBL
    A0A8M1P1T3, E7F5L8
    Related
    ENSDARP00000025759.7, ENSDART00000004782.8
    Conserved Domains (1) summary
    pfam04006
    Location:19 → 645
    Mpp10; Mpp10 protein

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007118.7 Reference GRCz11 Primary Assembly

    Range
    30772991..30779569 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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