U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

pask PAS domain containing serine/threonine kinase [ Danio rerio (zebrafish) ]

Gene ID: 322674, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
paskprovided by ZNC
Official Full Name
PAS domain containing serine/threonine kinaseprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-1394
See related
Ensembl:ENSDARG00000075008 AllianceGenome:ZFIN:ZDB-GENE-030131-1394
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
pas; wu:fb69h07; si:dkeyp-94h10.2
Summary
Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction and negative regulation of glycogen biosynthetic process. Predicted to act upstream of or within protein phosphorylation. Predicted to be active in cytosol and nucleus. Orthologous to human PASK (PAS domain containing serine/threonine kinase). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See pask in Genome Data Viewer
Location:
chromosome: 2
Exon count:
20
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 2 NC_007113.7 (44512359..44545869)
105 previous assembly GRCz10 (GCF_000002035.5) 2 NC_007113.6 (44659337..44692871)

Chromosome 2 - NC_007113.7Genomic Context describing neighboring genes Neighboring gene dynein axonemal assembly factor 6 Neighboring gene potassium voltage-gated channel subfamily A regulatory beta subunit 1b Neighboring gene uncharacterized LOC137488105 Neighboring gene probable G-protein coupled receptor 148 Neighboring gene mitochondrial transcription termination factor 4

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article
  2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein serine/threonine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in intracellular signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in negative regulation of glycogen biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within phosphorylation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within protein phosphorylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
PAS domain-containing serine/threonine-protein kinase
XP_003197983.1
XP_005171473.1
XP_021329605.2

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007113.7 Reference GRCz11 Primary Assembly

    Range
    44512359..44545869
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005171416.5 → XP_005171473.1  PAS domain-containing serine/threonine-protein kinase

    See identical proteins and their annotated locations for XP_005171473.1

    UniProtKB/TrEMBL
    A0A8M2BIR6, B0S5Z9
    Conserved Domains (2) summary
    smart00220
    Location:898 → 1150
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cl21453
    Location:898 → 1150
    PKc_like; Protein Kinases, catalytic domain

  2. XM_003197935.6 → XP_003197983.1  PAS domain-containing serine/threonine-protein kinase

    See identical proteins and their annotated locations for XP_003197983.1

    UniProtKB/TrEMBL
    A0A8M2BIR6, B0S5Z9
    Related
    ENSDARP00000129270.1, ENSDART00000156310.3
    Conserved Domains (2) summary
    smart00220
    Location:898 → 1150
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cl21453
    Location:898 → 1150
    PKc_like; Protein Kinases, catalytic domain

Reference GRCz11 ALT_DRER_TU_2

Genomic

  1. NW_018395223.1 Reference GRCz11 ALT_DRER_TU_2

    Range
    363155..389825
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021473930.2 → XP_021329605.2  PAS domain-containing serine/threonine-protein kinase

Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools