U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Inpp1 inositol polyphosphate-1-phosphatase [ Rattus norvegicus (Norway rat) ]

Gene ID: 316376, updated on 14-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
Inpp1provided by RGD
Official Full Name
inositol polyphosphate-1-phosphataseprovided by RGD
Primary source
RGD:1306071
See related
EnsemblRapid:ENSRNOG00000012375 AllianceGenome:RGD:1306071
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable inositol-1,4-bisphosphate 1-phosphatase activity. Predicted to be involved in phosphatidylinositol phosphate biosynthetic process. Orthologous to human INPP1 (inositol polyphosphate-1-phosphatase). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Kidney (RPKM 68.7), Lung (RPKM 61.9) and 9 other tissues See more
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Inpp1 in Genome Data Viewer
Location:
9q22
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (56161816..56209774)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (48688037..48717793)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (53544602..53574303)

Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene serine and arginine rich splicing factor 7, pseudogene 4 Neighboring gene 3-hydroxyisobutyryl-CoA hydrolase Neighboring gene post-GPI attachment to proteins 2, pseudogene 2 Neighboring gene BCL2 interacting protein 3, pseudogene 1

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in phosphatidylinositol phosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
inositol polyphosphate 1-phosphatase
NP_001012131.1
XP_006244961.1
XP_008765313.1
XP_008765314.1
XP_038939520.1
XP_038939523.1
XP_063123238.1
XP_063123239.1
XP_063123240.1
XP_063123242.1
XP_063123243.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001012131.2 → NP_001012131.1  inositol polyphosphate 1-phosphatase isoform 1

    See identical proteins and their annotated locations for NP_001012131.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000009
    UniProtKB/TrEMBL
    A0A8I6ALU7, A0A8I6GJG8, A6INV6, Q5RJK6
    Related
    ENSRNOP00000091276.1, ENSRNOT00000112625.2
    Conserved Domains (1) summary
    cd01640
    Location:4 → 384
    IPPase; Inositol polyphosphate-1-phosphatase, a member of the Mg++ dependent family of inositol monophosphatase-like domains, hydrolyzes the 1' position phosphate from inositol 1,3,4-trisphosphate and inositol 1,4-bisphosphate. Members in this group may also ...

  2. NM_001432655.1 → NP_001419584.1  inositol polyphosphate 1-phosphatase isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000009
    UniProtKB/TrEMBL
    A0A8I6ALU7, A6INV6, Q5RJK6

  3. NM_001432664.1 → NP_001419593.1  inositol polyphosphate 1-phosphatase isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000009
    UniProtKB/TrEMBL
    A0A8I6ALU7, A6INV6, Q5RJK6

  4. NM_001432665.1 → NP_001419594.1  inositol polyphosphate 1-phosphatase isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000009
    UniProtKB/TrEMBL
    A0A8I6ALU7, A6INV6, Q5RJK6

  5. NM_001432666.1 → NP_001419595.1  inositol polyphosphate 1-phosphatase isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000009
    UniProtKB/TrEMBL
    A0A8I6ALU7, A6INV6, Q5RJK6

  6. NM_001432667.1 → NP_001419596.1  inositol polyphosphate 1-phosphatase isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000009
    UniProtKB/TrEMBL
    A0A8I6ALU7, A6INV6, Q5RJK6

  7. NM_001432668.1 → NP_001419597.1  inositol polyphosphate 1-phosphatase isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000009
    UniProtKB/TrEMBL
    A0A8I6ALU7, A6INV6, Q5RJK6

  8. NM_001432669.1 → NP_001419598.1  inositol polyphosphate 1-phosphatase isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000009
    UniProtKB/TrEMBL
    A0A8I6ALU7, A6INV6, Q5RJK6

  9. NM_001432670.1 → NP_001419599.1  inositol polyphosphate 1-phosphatase isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000009

  10. NM_001432671.1 → NP_001419600.1  inositol polyphosphate 1-phosphatase isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000009

  11. NM_001432672.1 → NP_001419601.1  inositol polyphosphate 1-phosphatase isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000009

  12. NM_001432673.1 → NP_001419602.1  inositol polyphosphate 1-phosphatase isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000009

  13. NM_001432674.1 → NP_001419603.1  inositol polyphosphate 1-phosphatase isoform 3

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000009

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086027.1 Reference GRCr8

    Range
    56161816..56209774
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063267168.1 → XP_063123238.1  inositol polyphosphate 1-phosphatase isoform X1

    UniProtKB/TrEMBL
    F7FA04
    Related
    ENSRNOP00000016842.5, ENSRNOT00000016842.7

  2. XM_063267169.1 → XP_063123239.1  inositol polyphosphate 1-phosphatase isoform X3

  3. XM_039083592.2 → XP_038939520.1  inositol polyphosphate 1-phosphatase isoform X2

    Conserved Domains (1) summary
    cd01640
    Location:4 → 384
    IPPase; Inositol polyphosphate-1-phosphatase, a member of the Mg++ dependent family of inositol monophosphatase-like domains, hydrolyzes the 1' position phosphate from inositol 1,3,4-trisphosphate and inositol 1,4-bisphosphate. Members in this group may also ...

  4. XM_063267170.1 → XP_063123240.1  inositol polyphosphate 1-phosphatase isoform X4

  5. XM_039083595.2 → XP_038939523.1  inositol polyphosphate 1-phosphatase isoform X5

    Conserved Domains (1) summary
    cl00289
    Location:48 → 276
    FIG; FBPase/IMPase/glpX-like domain. A superfamily of metal-dependent phosphatases with various substrates. Fructose-1,6-bisphospatase (both the major and the glpX-encoded variant) hydrolyze fructose-1,6,-bisphosphate to fructose-6-phosphate in ...

  6. XM_006244899.5 → XP_006244961.1  inositol polyphosphate 1-phosphatase isoform X2

    Related
    ENSRNOP00000096460.1, ENSRNOT00000109452.2
    Conserved Domains (1) summary
    cd01640
    Location:4 → 384
    IPPase; Inositol polyphosphate-1-phosphatase, a member of the Mg++ dependent family of inositol monophosphatase-like domains, hydrolyzes the 1' position phosphate from inositol 1,3,4-trisphosphate and inositol 1,4-bisphosphate. Members in this group may also ...

  7. XM_008767092.3 → XP_008765314.1  inositol polyphosphate 1-phosphatase isoform X2

    Conserved Domains (1) summary
    cd01640
    Location:4 → 384
    IPPase; Inositol polyphosphate-1-phosphatase, a member of the Mg++ dependent family of inositol monophosphatase-like domains, hydrolyzes the 1' position phosphate from inositol 1,3,4-trisphosphate and inositol 1,4-bisphosphate. Members in this group may also ...

  8. XM_063267172.1 → XP_063123242.1  inositol polyphosphate 1-phosphatase isoform X4

  9. XM_063267173.1 → XP_063123243.1  inositol polyphosphate 1-phosphatase isoform X4

  10. XM_008767091.4 → XP_008765313.1  inositol polyphosphate 1-phosphatase isoform X2

    Conserved Domains (1) summary
    cd01640
    Location:4 → 384
    IPPase; Inositol polyphosphate-1-phosphatase, a member of the Mg++ dependent family of inositol monophosphatase-like domains, hydrolyzes the 1' position phosphate from inositol 1,3,4-trisphosphate and inositol 1,4-bisphosphate. Members in this group may also ...
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools