U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

GP second secreted glycoprotein;small secreted glycoprotein;spike glycoprotein [ Sudan ebolavirus ]

Gene ID: 3160774, updated on 18-Aug-2023

Summary

Go to the top of the page Help
Gene symbol
GP
Gene description
second secreted glycoprotein;small secreted glycoprotein;spike glycoprotein
Locus tag
SEVgp4
Gene type
protein coding
RNA name
sGP
RefSeq status
PROVISIONAL
Organism
Sudan ebolavirus (isolate: Sudan virus/H.sapiens-tc/UGA/2000/Gulu-808892)
Lineage
Viruses; ssRNA viruses; ssRNA negative-strand viruses; Mononegavirales; Filoviridae; Ebolavirus
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Sequence:
NC_006432.1 (5883..8241)

NC_006432.1Genomic Context describing neighboring genes Neighboring gene nucleoprotein Neighboring gene polymerase complex protein Neighboring gene matrix protein Neighboring gene minor nucleoprotein Neighboring gene membrane-associated protein Neighboring gene RNA-dependent RNA polymerase

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_006432.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Complete genome sequence of an Ebola virus (Sudan species) responsible for a 2000 outbreak of human disease in Uganda. Sanchez A, et al. Virus Res, 2005 Oct. PMID 16139097

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Miscellaneous features

  • Loc: 6877-6883 transcription editing site; polymerase slippage of 1 nucleotide (-1 direction) during transcription results in the addition of an extra adenosine and the translation of an altenate frame leading to expression of GP

regulatory

  • Loc: 8224-8235 regulatory_class = other
  • Loc: 8231-8241 regulatory_class = polyA_signal_sequence

General protein information

Go to the top of the page Help
Preferred Names
second secreted glycoprotein;small secreted glycoprotein;spike glycoprotein
YP_009246341.1
  • second non-structural secreted glycoprotein; super small secreted glycoprotein; secreted in a monomeric form; one A residue is deleted or two additional A residues are inserted at the editing site during transcription of the GP gene
YP_138523.1
  • structural glycoprotein; processed by furin to yield GP1-GP2 heterodimer that forms membrane-anchored trimers (peplomers)
YP_138524.1
  • small non-structural secreted glycoprotein; forms dimers linked by disulfide bonds (parallel orientation); processed by furin to yield sGP and delta peptide; sGP

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_006432.1 Reference assembly

    Range
    5883..8241
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. YP_138523.1 spike glycoprotein [Sudan ebolavirus]

    See identical proteins and their annotated locations for YP_138523.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q7T9D9
    UniProtKB/TrEMBL
    A0A0E3KN50, I7F2J9
    Conserved Domains (3) summary
    cd09850
    Location:557 → 629
    Ebola-like_HR1-HR2; heptad repeat 1-heptad repeat 2 region of the transmembrane subunit of Filoviridae viruses, Ebola virus and Marburg virus, and related domains
    pfam01611
    Location:15 → 347
    Filo_glycop; Filovirus glycoprotein
    pfam15324
    Location:309 → 487
    TALPID3; Hedgehog signalling target

  2. YP_138524.1 small secreted glycoprotein [Sudan ebolavirus]

    See identical proteins and their annotated locations for YP_138524.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q7T9E0
    UniProtKB/TrEMBL
    A0A0E3NBA8, B0LPL8, I7FLM2
    Conserved Domains (1) summary
    pfam01611
    Location:15 → 295
    Filo_glycop; Filovirus glycoprotein

  3. YP_009246341.1 second secreted glycoprotein [Sudan ebolavirus]

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P0C772
    UniProtKB/TrEMBL
    A0A0E3H7J8, A0A2U8KL62
    Conserved Domains (1) summary
    pfam01611
    Location:15 → 295
    Filo_glycop; Filovirus glycoprotein
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials