U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Tecpr2 tectonin beta-propeller repeat containing 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 314456, updated on 17-Aug-2024

Summary

Go to the top of the page Help
Official Symbol
Tecpr2provided by RGD
Official Full Name
tectonin beta-propeller repeat containing 2provided by RGD
Primary source
RGD:1307503
See related
EnsemblRapid:ENSRNOG00000021904 AllianceGenome:RGD:1307503
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1307503
Summary
Predicted to be involved in protein exit from endoplasmic reticulum. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 49. Orthologous to human TECPR2 (tectonin beta-propeller repeat containing 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Brain (RPKM 82.6), Adrenal (RPKM 53.0) and 9 other tissues See more
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Tecpr2 in Genome Data Viewer
Location:
6q32
Exon count:
24
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (135720765..135823187)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (129899541..130001975)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (135304536..135405865)

Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108351302 Neighboring gene transfer RNA isoleucine (anticodon AAU) 3 Neighboring gene zinc finger protein 839 Neighboring gene cyclin-dependent kinase 2-interacting protein Neighboring gene uncharacterized LOC134479258 Neighboring gene ankyrin repeat domain 9 Neighboring gene uncharacterized LOC134479478

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. TECPR2 Cooperates with LC3C to Regulate COPII-Dependent ER Export. Stadel D, et al. Mol Cell, 2015 Oct 1. PMID 26431026
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in protein exit from endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein exit from endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
tectonin beta-propeller repeat-containing protein 2

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001427221.1 → NP_001414150.1  tectonin beta-propeller repeat-containing protein 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000006
    UniProtKB/TrEMBL
    D4A6U4
    Related
    ENSRNOP00000035369.5, ENSRNOT00000030864.8

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086024.1 Reference GRCr8

    Range
    135720765..135823187
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063262024.1 → XP_063118094.1  tectonin beta-propeller repeat-containing protein 2 isoform X2

    Related
    ENSRNOP00000103146.1, ENSRNOT00000142113.1

  2. XM_063262025.1 → XP_063118095.1  tectonin beta-propeller repeat-containing protein 2 isoform X5

  3. XM_006240620.4 → XP_006240682.1  tectonin beta-propeller repeat-containing protein 2 isoform X3

    See identical proteins and their annotated locations for XP_006240682.1

    Related
    ENSRNOP00000099871.1, ENSRNOT00000128256.1
    Conserved Domains (2) summary
    pfam06462
    Location:864 → 894
    Hyd_WA; Propeller
    pfam19193
    Location:1046 → 1240
    Tectonin; Tectonin domain

  4. XM_039113381.2 → XP_038969309.1  tectonin beta-propeller repeat-containing protein 2 isoform X3

    Conserved Domains (2) summary
    pfam06462
    Location:864 → 894
    Hyd_WA; Propeller
    pfam19193
    Location:1046 → 1240
    Tectonin; Tectonin domain

  5. XM_008764970.4 → XP_008763192.1  tectonin beta-propeller repeat-containing protein 2 isoform X1

    See identical proteins and their annotated locations for XP_008763192.1

    UniProtKB/TrEMBL
    D4A6U4
    Conserved Domains (4) summary
    COG2319
    Location:36 → 366
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:37 → 73
    7WD40; WD40 repeat [structural motif]
    pfam06462
    Location:1003 → 1033
    Hyd_WA; Propeller
    pfam19193
    Location:1185 → 1379
    Tectonin; Tectonin domain

  6. XM_039113382.2 → XP_038969310.1  tectonin beta-propeller repeat-containing protein 2 isoform X3

    Conserved Domains (2) summary
    pfam06462
    Location:864 → 894
    Hyd_WA; Propeller
    pfam19193
    Location:1046 → 1240
    Tectonin; Tectonin domain

  7. XM_039113379.2 → XP_038969307.1  tectonin beta-propeller repeat-containing protein 2 isoform X1

    UniProtKB/TrEMBL
    D4A6U4
    Conserved Domains (4) summary
    COG2319
    Location:36 → 366
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:37 → 73
    7WD40; WD40 repeat [structural motif]
    pfam06462
    Location:1003 → 1033
    Hyd_WA; Propeller
    pfam19193
    Location:1185 → 1379
    Tectonin; Tectonin domain

  8. XM_008764972.4 → XP_008763194.1  tectonin beta-propeller repeat-containing protein 2 isoform X3

    See identical proteins and their annotated locations for XP_008763194.1

    Conserved Domains (2) summary
    pfam06462
    Location:864 → 894
    Hyd_WA; Propeller
    pfam19193
    Location:1046 → 1240
    Tectonin; Tectonin domain

  9. XM_039113383.2 → XP_038969311.1  tectonin beta-propeller repeat-containing protein 2 isoform X4

    Conserved Domains (2) summary
    pfam06462
    Location:636 → 666
    Hyd_WA; Propeller
    pfam19193
    Location:818 → 1012
    Tectonin; Tectonin domain

RNA

  1. XR_010052098.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools