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Rft1 RFT1 homolog [ Rattus norvegicus (Norway rat) ]

Gene ID: 290552, updated on 18-Sep-2024

Summary

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Official Symbol
Rft1provided by RGD
Official Full Name
RFT1 homologprovided by RGD
Primary source
RGD:1562654
See related
EnsemblRapid:ENSRNOG00000021805 AllianceGenome:RGD:1562654
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1562654
Summary
Predicted to be involved in glycolipid translocation. Predicted to be integral component of membrane. Predicted to be active in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation In. Orthologous to human RFT1 (RFT1 homolog). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Adrenal (RPKM 70.3), Kidney (RPKM 55.3) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Rft1 in Genome Data Viewer
Location:
16p16
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 16 NC_086034.1 (5833521..5867578)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 16 NC_051351.1 (5827063..5861120)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 16 NC_005115.4 (6712387..6746711)

Chromosome 16 - NC_086034.1Genomic Context describing neighboring genes Neighboring gene protein kinase C, delta Neighboring gene uncharacterized LOC134482445 Neighboring gene uncharacterized LOC134482446 Neighboring gene small nucleolar RNA SNORA32 Neighboring gene farnesyl diphosphate synthase, pseudogene 1 Neighboring gene Scm-like with four mbt domains 1 Neighboring gene small nucleolar RNA SNORD113/SNORD114 family

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in dolichol-linked oligosaccharide biosynthetic process ISO
Inferred from Sequence Orthology
more info
  
involved_in glycolipid translocation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in glycolipid translocation ISO
Inferred from Sequence Orthology
more info
  
involved_in protein N-linked glycosylation ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in endoplasmic reticulum membrane ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
protein RFT1 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001135866.1 → NP_001129338.1  protein RFT1 homolog

    Status: PROVISIONAL

    Source sequence(s)
    JAXUCZ010000016
    UniProtKB/TrEMBL
    A6KG28, D4A6W4
    Related
    ENSRNOP00000035354.4, ENSRNOT00000035542.6
    Conserved Domains (1) summary
    pfam04506
    Location:11 → 524
    Rft-1; Rft protein

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086034.1 Reference GRCr8

    Range
    5833521..5867578
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006252581.5 → XP_006252643.1  protein RFT1 homolog isoform X1

    UniProtKB/TrEMBL
    A6KG28
    Related
    ENSRNOP00000106442.1, ENSRNOT00000152898.1
    Conserved Domains (1) summary
    pfam04506
    Location:11 → 486
    Rft-1; Rft protein

  2. XM_039094264.2 → XP_038950192.1  protein RFT1 homolog isoform X2

    Conserved Domains (1) summary
    cl09326
    Location:14 → 405
    MATE_like; Multidrug and toxic compound extrusion family and similar proteins

  3. XM_063275133.1 → XP_063131203.1  protein RFT1 homolog isoform X3

RNA

  1. XR_005494551.2 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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