Krt15 keratin 15 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Krt15provided by RGD
Official Full Name: keratin 15provided by RGD
Primary source: RGD:1303044
See related: EnsemblRapid:ENSRNOG00000071325 AllianceGenome:RGD:1303044
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Ka15
Summary: Predicted to enable scaffold protein binding activity. Predicted to be involved in epithelial cell differentiation and intermediate filament organization. Predicted to be located in keratin filament. Predicted to be active in cytoskeleton. Orthologous to human KRT15 (keratin 15). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in Lung (RPKM 125.5), Thymus (RPKM 67.0) and 2 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 10q31

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	10	NC_086028.1 (85567197..85571014, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	10	NC_051345.1 (85066797..85070614, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	10	NC_005109.4 (88046803..88050622, complement)

Chromosome 10 - NC_086028.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

AI528832 (e-PCR)
- UniSTS:180315

Krt15 (e-PCR), detects polymorphism
- UniSTS:474754

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables scaffold protein binding	ISO Inferred from Sequence Orthology more info
enables structural constituent of cytoskeleton	TAS Traceable Author Statement more info	PubMed

Process	Evidence Code	Pubs
involved_in epithelial cell differentiation	IBA Inferred from Biological aspect of Ancestor more info
involved_in intermediate filament organization	IBA Inferred from Biological aspect of Ancestor more info
involved_in intermediate filament-based process	TAS Traceable Author Statement more info	PubMed

Component	Evidence Code	Pubs
is_active_in cytoskeleton	IBA Inferred from Biological aspect of Ancestor more info
located_in intermediate filament	TAS Traceable Author Statement more info	PubMed
located_in keratin filament	TAS Traceable Author Statement more info	PubMed

General protein information

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Preferred Names: keratin, type I cytoskeletal 15

Names: CK-15; K15; cytokeratin-15; keratin 15, type I; type I keratin KA15

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.