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GLRA1 glycine receptor alpha 1 [ Bos taurus (domestic cattle) ]

Gene ID: 281783, updated on 17-Aug-2024

Summary

Official Symbol
GLRA1provided by VGNC
Official Full Name
glycine receptor alpha 1provided by VGNC
Primary source
VGNC:VGNC:29412
See related
BGD:BT12218; Ensembl:ENSBTAG00000014395
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
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Genomic context

See GLRA1 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 7 NC_037334.1 (63021619..63108191, complement)

Chromosome 7 - NC_037334.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC112447461 Neighboring gene antioxidant 1 copper chaperone Neighboring gene G3BP stress granule assembly factor 1 Neighboring gene uncharacterized LOC132345775 Neighboring gene neuromedin U receptor 2 Neighboring gene small ribosomal subunit protein uS3-like

Genomic regions, transcripts, and products

Genomic Sequence:
NC_037334.1 Chromosome 7 Reference ARS-UCD2.0 Primary Assembly

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables extracellularly glycine-gated chloride channel activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables glycine binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables transmembrane signaling receptor activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables transmitter-gated monoatomic ion channel activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in chemical synaptic transmission IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in chloride transmembrane transport IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in nervous system process IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in regulation of membrane potential IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in neuron projection IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in postsynaptic membrane IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in synapse IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
glycine receptor subunit alpha-1
Names
glycine receptor 48 kDa subunit
glycine receptor alpha 1 subunit
glycine receptor strychnine-binding subunit
glycine receptor, alpha 1 (startle disease/hyperekplexia)
glycine receptor, alpha 1 (startle disease/hyperekplexia, stiff man syndrome)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_174321.2NP_776746.1  glycine receptor subunit alpha-1 precursor

    See identical proteins and their annotated locations for NP_776746.1

    Status: PROVISIONAL

    Source sequence(s)
    AF268375
    UniProtKB/Swiss-Prot
    P57695, Q9GKE9, Q9GKF0
    Related
    ENSBTAP00000019143.3, ENSBTAT00000019143.4
    Conserved Domains (1) summary
    TIGR00860
    Location:7446
    LIC; Cation transporter family protein

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037334.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    63021619..63108191 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)