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Nop16 NOP16 nucleolar protein [ Mus musculus (house mouse) ]

Gene ID: 28126, updated on 2-Nov-2024

Summary

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Official Symbol
Nop16provided by MGI
Official Full Name
NOP16 nucleolar proteinprovided by MGI
Primary source
MGI:MGI:107862
See related
Ensembl:ENSMUSG00000025869 AllianceGenome:MGI:107862
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
D13Wsu177e
Summary
Predicted to be involved in ribosomal large subunit biogenesis. Predicted to be located in nucleoplasm. Predicted to be active in nucleolus. Is expressed in embryo and extraembryonic component. Orthologous to human NOP16 (NOP16 nucleolar protein). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Ubiquitous expression in liver E14 (RPKM 14.3), CNS E11.5 (RPKM 12.5) and 26 other tissues See more
Orthologs
human all
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Genomic context

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See Nop16 in Genome Data Viewer
Location:
13 B1; 13 28.83 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (54732004..54737921, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (54584191..54590097, complement)

Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene SUMO-interacting motifs containing 1 Neighboring gene RIKEN cDNA 4833439L19 gene Neighboring gene CapStarr-seq enhancer MGSCv37_chr13:54666808-54666917 Neighboring gene ADP-ribosylation factor-like 10 Neighboring gene predicted gene, 24195 Neighboring gene STARR-positive B cell enhancer ABC_E927 Neighboring gene HIG1 domain family, member 2A Neighboring gene clathrin light chain B Neighboring gene STARR-seq mESC enhancer starr_34588 Neighboring gene STARR-seq mESC enhancer starr_34589

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Molecular characterizations of Nop16 in murine mammary tumors with varying levels of c-Myc. Kundel DW, et al. Transgenic Res, 2012 Apr. PMID 21863248, Free PMC Article
  2. Beads-free protein immunoprecipitation for a mass spectrometry-based interactome and posttranslational modifications analysis. Mikula M, et al. Proteome Sci, 2015. PMID 26336360, Free PMC Article
  3. Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome. Ko MS, et al. Hum Mol Genet, 1998 Nov. PMID 9811942
  4. Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics. Federspiel JD, et al. Mol Cell Proteomics, 2019 Aug 9. PMID 31040226, Free PMC Article
  5. Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells. Zhang S, et al. Sci Data, 2018 Nov 20. PMID 30457570, Free PMC Article

See all (22) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Process Evidence Code Pubs
involved_in ribosomal large subunit biogenesis IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
  
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
  
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
  
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
nucleolar protein 16
Names
NOP16 nucleolar protein homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_178605.4 → NP_848720.1  nucleolar protein 16

    See identical proteins and their annotated locations for NP_848720.1

    Status: PROVISIONAL

    Source sequence(s)
    AC155262
    Consensus CDS
    CCDS26531.1
    UniProtKB/Swiss-Prot
    Q8C2P2, Q921K0, Q9CPT5
    UniProtKB/TrEMBL
    D3Z7M5
    Related
    ENSMUSP00000026987.6, ENSMUST00000026987.12
    Conserved Domains (2) summary
    pfam09420
    Location:20 → 153
    Nop16; Ribosome biogenesis protein Nop16
    cl21456
    Location:143 → 177
    Periplasmic_Binding_Protein_Type_2; Type 2 periplasmic binding fold superfamily

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000079.7 Reference GRCm39 C57BL/6J

    Range
    54732004..54737921 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030247292.2 → XP_030103152.1  nucleolar protein 16 isoform X1

    Conserved Domains (1) summary
    pfam09420
    Location:20 → 65
    Nop16; Ribosome biogenesis protein Nop16
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9CPT5.1 GenPept UniProtKB/Swiss-Prot:Q9CPT5

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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