INHA inhibin subunit alpha [Bos taurus (domestic cattle)] - Gene

Summary

Official Symbol: INHAprovided by VGNC
Official Full Name: inhibin subunit alphaprovided by VGNC
Primary source: VGNC:VGNC:30199
See related: BGD:BT10872; Ensembl:ENSBTAG00000009972
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 2

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2023_09	current	ARS-UCD2.0 (GCF_002263795.3)	2	NC_037329.1 (107501829..107504802)

Chromosome 2 - NC_037329.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037329.1 Chromosome 2 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The effects of castration and other surgical intervention on the blood levels of anti-Muellerian hormone, inhibin A, gonadotropins, and gonadotropin receptors in bull calves are reported.
Title: Anti-Muellerian hormone, inhibin A, gonadotropins, and gonadotropin receptors in bull calves after partial scrotal resection, orchidectomy, and Burdizzo castration.
The expression of the components of the activin-inhibin-follistatin system is altered in bovine cystic ovarian disease.
Title: Role of activin, inhibin, and follistatin in the pathogenesis of bovine cystic ovarian disease.
INHA gene can be used as a predictor for superovulation in Chinese Holstein cows.
Title: An MspI polymorphism in the inhibin alpha gene and its associations with superovulation traits in Chinese Holstein cows.
overexpression of inhibin alpha (1-32) fragment regulated granulosa cell development and effects on subsequent oocyte maturation were both time- and stage-dependent
Title: Effect of overexpression of inhibin alpha (1-32) fragment on bovine granulosa cell proliferation, apoptosis, steroidogenesis, and development of co-cultured oocytes.
Inhibin has a negative autocrine or paracrine effect on the in vitro capacity of granulosa cells isolated from dominant or subordinate follicles to produce estradiol.
Title: Evidence for a negative intrafollicular role for inhibin in regulation of estradiol production by granulosa cells.

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General gene information

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Markers

REN53413 (e-PCR)
- UniSTS:378213

REN53416 (e-PCR)
- UniSTS:378216

INHA (e-PCR), detects polymorphism
- UniSTS:519077

UniSTS:143587 (e-PCR)
- UniSTS:143587

Inha (e-PCR), detects polymorphism
- UniSTS:143587

ECD17211 (e-PCR)
- UniSTS:298224

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables cytokine activity	IEA Inferred from Electronic Annotation more info	PubMed
enables growth factor activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in SMAD protein signal transduction	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in extracellular region	IEA Inferred from Electronic Annotation more info	PubMed
located_in extracellular space	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: inhibin alpha chain

Names: inhibin A; inhibin alpha subunit; inhibin, alpha

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.