U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

GFAP glial fibrillary acidic protein [ Bos taurus (domestic cattle) ]

Gene ID: 281189, updated on 12-Oct-2024

Summary

Go to the top of the page Help
Official Symbol
GFAPprovided by VGNC
Official Full Name
glial fibrillary acidic proteinprovided by VGNC
Primary source
VGNC:VGNC:29323
See related
BGD:BT10734; Ensembl:ENSBTAG00000013534
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See GFAP in Genome Data Viewer
Location:
chromosome: 19
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 19 NC_037346.1 (44611312..44620648, complement)

Chromosome 19 - NC_037346.1Genomic Context describing neighboring genes Neighboring gene elongation factor Tu GTP binding domain containing 2 Neighboring gene microRNA mir-2343 Neighboring gene coiled-coil domain containing 103 Neighboring gene family with sequence similarity 187 member A Neighboring gene kinesin family member 18B Neighboring gene uncharacterized LOC104975097 Neighboring gene complement C1q like 1

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_037346.1 Chromosome 19 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Use of a heterologous monoclonal antibody for cloning and detection of glial fibrillary acidic protein in the bovine ventricular ependyma. Bouchard P, et al. Cell Tissue Res, 1999 Nov. PMID 10571109
  2. Conformation polymorphisms and targeted marker development. Kirkpatrick BW, et al. Anim Genet, 1994 Apr. PMID 8010535
  3. Substrate preference and phosphatidylinositol monophosphate inhibition of the catalytic domain of the Per-Arnt-Sim domain kinase PASKIN. Schläfli P, et al. FEBS J, 2011 May. PMID 21418524
  4. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  5. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

Go to the top of the page

General gene information

Go to the top of the page Help

Markers

Homology

Clone Names

  • MGC139638

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables structural constituent of cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intermediate filament organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of chaperone-mediated autophagy IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cell projection IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in intermediate filament IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
glial fibrillary acidic protein

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_174065.2 → NP_776490.2  glial fibrillary acidic protein

    See identical proteins and their annotated locations for NP_776490.2

    Status: PROVISIONAL

    Source sequence(s)
    BC119892
    UniProtKB/Swiss-Prot
    Q0P5L4, Q28115, Q866S9
    UniProtKB/TrEMBL
    A0A3Q1MVU3
    Related
    ENSBTAP00000017997.4, ENSBTAT00000017997.5
    Conserved Domains (2) summary
    pfam00038
    Location:64 → 372
    Filament; Intermediate filament protein
    pfam04732
    Location:3 → 62
    Filament_head; Intermediate filament head (DNA binding) region

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037346.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    44611312..44620648 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_010816312.4 → XP_010814614.1  glial fibrillary acidic protein isoform X1

    UniProtKB/TrEMBL
    A0A3Q1MHT3, A0A3Q1MVU3
    Related
    ENSBTAP00000073843.2, ENSBTAT00000071297.2
    Conserved Domains (2) summary
    pfam00038
    Location:64 → 372
    Filament; Intermediate filament protein
    pfam04732
    Location:3 → 62
    Filament_head; Intermediate filament head (DNA binding) region
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q28115.2 GenPept UniProtKB/Swiss-Prot:Q28115

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.