U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

CDK1 cyclin dependent kinase 1 [ Bos taurus (domestic cattle) ]

Gene ID: 281061, updated on 17-Aug-2024

Summary

Go to the top of the page Help
Official Symbol
CDK1provided by VGNC
Official Full Name
cyclin dependent kinase 1provided by VGNC
Primary source
VGNC:VGNC:27115
See related
BGD:BT30042; Ensembl:ENSBTAG00000010109
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as
CDC2
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See CDK1 in Genome Data Viewer
Location:
chromosome: 28
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 28 NC_037355.1 (16488151..16539563)

Chromosome 28 - NC_037355.1Genomic Context describing neighboring genes Neighboring gene ankyrin 3 Neighboring gene transfer RNA glycine (anticodon UCC) Neighboring gene U6 spliceosomal RNA Neighboring gene ferritin heavy chain-like Neighboring gene uncharacterized LOC132344129 Neighboring gene Rho related BTB domain containing 1

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_037355.1 Chromosome 28 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Identification of cDNAs encoding bovine cyclin B and Cdk1/Cdc2. Yang L, et al. Gene, 1994 Apr 20. PMID 8163203
  2. Oligosaccharides of hyaluronan induce angiogenesis through distinct CD44 and RHAMM-mediated signalling pathways involving Cdc2 and gamma-adducin. Matou-Nasri S, et al. Int J Oncol, 2009 Oct. PMID 19724912
  3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Oligosaccharides of hyaluronan induce angiogenesis through distinct CD44 and RHAMM-mediated signalling pathways involving Cdc2 and gamma-adducin.
    Title: Oligosaccharides of hyaluronan induce angiogenesis through distinct CD44 and RHAMM-mediated signalling pathways involving Cdc2 and gamma-adducin.
Submit: New GeneRIF Correction

Pathways from PubChem

Go to the top of the page

General gene information

Go to the top of the page Help

Markers

Homology

Clone Names

  • MGC134454

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II CTD heptapeptide repeat kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cyclin-dependent protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in G2/M transition of mitotic cell cycle IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in mitotic G2 DNA damage checkpoint signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
cyclin-dependent kinase 1
Names
cell division control protein 2 homolog
cell division cycle 2, G1 to S and G2 to M
cell division protein kinase 1
p34 protein kinase
NP_776441.1
XP_005226354.1
XP_005226356.1
XP_010818803.1
XP_024842276.1
XP_059738393.1
XP_059738394.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_174016.2 → NP_776441.1  cyclin-dependent kinase 1

    See identical proteins and their annotated locations for NP_776441.1

    Status: PROVISIONAL

    Source sequence(s)
    L26547
    UniProtKB/TrEMBL
    A0AAA9TH51
    Related
    ENSBTAP00000013337.2, ENSBTAT00000013337.4
    Conserved Domains (2) summary
    PLN00009
    Location:1 → 293
    PLN00009; cyclin-dependent kinase A; Provisional
    cd07861
    Location:3 → 287
    STKc_CDK1_euk; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 1 from higher eukaryotes

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037355.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    16488151..16539563
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005226297.5 → XP_005226354.1  cyclin-dependent kinase 1 isoform X1

    See identical proteins and their annotated locations for XP_005226354.1

    UniProtKB/Swiss-Prot
    P48734, Q2YDM6
    UniProtKB/TrEMBL
    A0AAA9TH51
    Conserved Domains (1) summary
    cd07861
    Location:3 → 287
    STKc_CDK1_euk; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 1 from higher eukaryotes

  2. XM_010820501.4 → XP_010818803.1  cyclin-dependent kinase 1 isoform X3

    See identical proteins and their annotated locations for XP_010818803.1

    UniProtKB/TrEMBL
    A0AAA9TH51
    Conserved Domains (2) summary
    PLN00009
    Location:1 → 267
    PLN00009; cyclin-dependent kinase A; Provisional
    cl21453
    Location:3 → 267
    PKc_like; Protein Kinases, catalytic domain

  3. XM_059882411.1 → XP_059738394.1  cyclin-dependent kinase 1 isoform X4

    UniProtKB/TrEMBL
    A0AAA9TH51

  4. XM_005226299.4 → XP_005226356.1  cyclin-dependent kinase 1 isoform X1

    See identical proteins and their annotated locations for XP_005226356.1

    UniProtKB/Swiss-Prot
    P48734, Q2YDM6
    UniProtKB/TrEMBL
    A0AAA9TH51
    Conserved Domains (1) summary
    cd07861
    Location:3 → 287
    STKc_CDK1_euk; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 1 from higher eukaryotes

  5. XM_024986508.2 → XP_024842276.1  cyclin-dependent kinase 1 isoform X5

    UniProtKB/TrEMBL
    A0A3Q1MU67
    Related
    ENSBTAP00000058343.2, ENSBTAT00000076563.2
    Conserved Domains (1) summary
    cl21453
    Location:3 → 230
    PKc_like; Protein Kinases, catalytic domain

  6. XM_059882410.1 → XP_059738393.1  cyclin-dependent kinase 1 isoform X2

    UniProtKB/TrEMBL
    A0AAA9TH51
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P48734.2 GenPept UniProtKB/Swiss-Prot:P48734

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.