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moe1 translation initiation factor eIF3d [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2543412, updated on 22-Jun-2024

Summary

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Gene symbol
moe1
Gene description
translation initiation factor eIF3d
Locus tag
SPOM_SPAC637.07
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
tif304
Old locus tag
SPAC637.07
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Genomic context

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See moe1 in Genome Data Viewer
Location:
chromosome: I
Exon count:
1
Sequence:
Chromosome: I; NC_003424.3 (4551840..4553741)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene V-type ATPase V1 subunit B Neighboring gene ncRNA Neighboring gene alpha-1,2-galactosyltransferase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Fe-sulfur cluster assembly ATPase Nbp35 Neighboring gene putative ribonuclease H70

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A conserved interaction between Moe1 and Mal3 is important for proper spindle formation in Schizosaccharomyces pombe. Chen CR, et al. Mol Biol Cell, 2000 Dec. PMID 11102508, Free PMC Article
  2. Int6 and Moe1 interact with Cdc48 to regulate ERAD and proper chromosome segregation. Otero JH, et al. Cell Cycle, 2010 Jan 1. PMID 20016281, Free PMC Article
  3. Moe1 and spInt6, the fission yeast homologues of mammalian translation initiation factor 3 subunits p66 (eIF3d) and p48 (eIF3e), respectively, are required for stable association of eIF3 subunits. Bandyopadhyay A, et al. J Biol Chem, 2002 Jan 18. PMID 11705997
  4. A Transcript-Specific eIF3 Complex Mediates Global Translational Control of Energy Metabolism. Shah M, et al. Cell Rep, 2016 Aug 16. PMID 27477275, Free PMC Article
  5. Yin6, a fission yeast Int6 homolog, complexes with Moe1 and plays a role in chromosome segregation. Yen HC, et al. Proc Natl Acad Sci U S A, 2000 Dec 19. PMID 11121040, Free PMC Article

See all (24) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. A transcript-specific eIF3 complex mediates global translational control of energy metabolism.
    Title: A Transcript-Specific eIF3 Complex Mediates Global Translational Control of Energy Metabolism.
  2. Results suggest that Cdc48, Yin6 and Moe1 act in the same protein complex to concertedly control ERAD and chromosome segregation.
    Title: Int6 and Moe1 interact with Cdc48 to regulate ERAD and proper chromosome segregation.
Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables translation initiation factor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in formation of cytoplasmic translation initiation complex IC
Inferred by Curator
more info
 PubMed 
involved_in translational initiation IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasmic stress granule EXP
Inferred from Experiment
more info
 PubMed 
is_active_in cytosol HDA PubMed 
is_active_in cytosol IDA
Inferred from Direct Assay
more info
 PubMed 
part_of eukaryotic 43S preinitiation complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of eukaryotic translation initiation factor 3 complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of eukaryotic translation initiation factor 3 complex, eIF3e IDA
Inferred from Direct Assay
more info
 PubMed 
part_of eukaryotic translation initiation factor 3 complex, eIF3m IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
translation initiation factor eIF3d

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    4551840..4553741
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001020053.3 → NP_594625.1  translation initiation factor eIF3d [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_594625.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O94236
    Conserved Domains (1) summary
    pfam05091
    Location:5 → 547
    eIF-3_zeta; Eukaryotic translation initiation factor 3 subunit 7 (eIF-3)
Nucleotide Protein
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