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mal2 kinetochore protein mal2 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2542737, updated on 18-Sep-2024

Summary

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Official Symbol
mal2
Official Full Name
kinetochore protein mal2
Primary source
PomBase:SPAC25B8.14
Locus tag
SPOM_SPAC25B8.14
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See mal2 in Genome Data Viewer
Location:
chromosome: I
Exon count:
1
Sequence:
Chromosome: I; NC_003424.3 (4185282..4187416)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene 5S ribosomal RNA Neighboring gene wybutosine biosynthesis protein Tyw3 Neighboring gene Rnase P/MRP subunit Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene intramembrane aspartyl protease of the perinuclear ER membrane Ypf1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Fission yeast mal2+ is required for chromosome segregation. Fleig U, et al. Mol Cell Biol, 1996 Nov. PMID 8887647, Free PMC Article
  2. The mal2p protein is an essential component of the fission yeast centromere. Jin QW, et al. Mol Cell Biol, 2002 Oct. PMID 12242294, Free PMC Article
  3. Fta2, an essential fission yeast kinetochore component, interacts closely with the conserved Mal2 protein. Kerres A, et al. Mol Biol Cell, 2006 Oct. PMID 16855021, Free PMC Article
  4. Eic1 links Mis18 with the CCAN/Mis6/Ctf19 complex to promote CENP-A assembly. Subramanian L, et al. Open Biol, 2014 Apr 30. PMID 24789708, Free PMC Article
  5. The conserved Spc7 protein is required for spindle integrity and links kinetochore complexes in fission yeast. Kerres A, et al. Mol Biol Cell, 2007 Jul. PMID 17442892, Free PMC Article

See all (18) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in CENP-A containing chromatin assembly IC
Inferred by Curator
more info
  
involved_in mitotic sister chromatid segregation IC
Inferred by Curator
more info
  
Component Evidence Code Pubs
part_of Mis6-Sim4 complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of Mis6-Sim4 complex IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in condensed chromosome, centromeric region IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cytosol HDA PubMed 
is_active_in kinetochore IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
kinetochore protein mal2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    4185282..4187416
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001019903.3 → NP_594474.1  kinetochore protein mal2 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_594474.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q10290
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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