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tps1 alpha,alpha-trehalose-phosphate synthase (UDP-forming) [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2542660, updated on 18-Sep-2024

Summary

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Official Symbol
tps1
Official Full Name
alpha,alpha-trehalose-phosphate synthase (UDP-forming)
Primary source
PomBase:SPAC328.03
Locus tag
SPOM_SPAC328.03
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See tps1 in Genome Data Viewer
Location:
chromosome: I
Exon count:
1
Sequence:
Chromosome: I; NC_003424.3 (3479149..3481305)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ubiquitin-protein ligase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene AAA domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Trehalose-6-P synthase is dispensable for growth on glucose but not for spore germination in Schizosaccharomyces pombe. Blázquez MA, et al. J Bacteriol, 1994 Jul. PMID 8021171, Free PMC Article
  2. Trehalose synthesis is important for the acquisition of thermotolerance in Schizosaccharomyces pombe. Ribeiro MJ, et al. Mol Microbiol, 1997 Aug. PMID 9302019
  3. Trehalose-6P synthase is essential for trehalase activation triggered by glucose, nitrogen source or heat shock, but not by osmostress, in Schizosaccharomyces pombe. Cansado J, et al. Biochim Biophys Acta, 1998 Aug 24. PMID 9729425
  4. Accumulation of trehalose by overexpression of tps1, coding for trehalose-6-phosphate synthase, causes increased resistance to multiple stresses in the fission yeast schizosaccharomyces pombe. Soto T, et al. Appl Environ Microbiol, 1999 May. PMID 10223994, Free PMC Article
  5. Functional characterization of Schizosaccharomyces pombe neutral trehalase altered in phosphorylatable serine residues. Franco A, et al. Arch Microbiol, 2005 Sep. PMID 15965643

See all (23) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Lipids and Trehalose Actively Cooperate in Heat Stress Management of Schizosaccharomyces pombe.
    Title: Lipids and Trehalose Actively Cooperate in Heat Stress Management of Schizosaccharomyces pombe.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in ascospore formation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in cellular response to heat IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in trehalose biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in trehalose biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in trehalose metabolic process IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in trehalose metabolism in response to stress IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in trehalose metabolism in response to stress IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of alpha,alpha-trehalose-phosphate synthase complex (UDP-forming) IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of alpha,alpha-trehalose-phosphate synthase complex (UDP-forming) IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cytosol HDA PubMed 

General protein information

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Preferred Names
alpha,alpha-trehalose-phosphate synthase (UDP-forming)

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    3479149..3481305
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001019628.3 → NP_594205.1  alpha,alpha-trehalose-phosphate synthase (UDP-forming) [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_594205.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P40387, Q9P3U3
    Conserved Domains (2) summary
    cd03788
    Location:20 → 482
    GT1_TPS; Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a ...
    TIGR02400
    Location:20 → 483
    trehalose_OtsA; alpha,alpha-trehalose-phosphate synthase [UDP-forming]
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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Molecular Biology Databases
Research Materials